Klebsiella pneumoniae strain EuSCAPE_ES128

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES128 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. It exhibits a variety of cell arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. This strain is mesophilic, with an optimal growth temperature of 37°C. As a free-living organism, EuSCAPE_ES128 has a diverse ecological niche, being associated with various hosts, including Homo sapiens, Gallus gallus, and several others across different kingdoms, such as Metazoa and Viridiplantae. This broad host range highlights its versatility and adaptability to different biological environments. Clinically, Klebsiella pneumoniae strain EuSCAPE_ES128 is significant due to its association with a wide array of health effects in humans. These include severe infections such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The pathogenicity of this strain poses a considerable risk, especially in hospital settings, where it can lead to conditions like sepsis and neonatal infections. The presence of this strain in multiple hosts suggests potential zoonotic transmission pathways and underscores the importance of monitoring its epidemiology. Understanding the traits and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_ES128 can inform public health strategies aimed at controlling its spread and mitigating its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES128

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES128
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES128 genome assembly,

Gene Summary

Adenine Count

966845 bp

Thymine Count

963307 bp

Guanine Count

1310587 bp

Cytosine Count

1314382 bp

Genome Length

4555121 bp

Protein-coding Genes

4857 genes

Non-Coding Genes

178 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
HolinSAMEA3649444_04029Not AvailablePositive4296169 - 429651612620.1
Hypothetical proteinSAMEA3649444_04030Not AvailablePositive4296513 - 42967889657.37
Hypothetical proteinSAMEA3649444_04031Not AvailablePositive4297296 - 42974967232.53
dna gyrase subunit betaSAMEA3649444_04032Not AvailablePositive4298237 - 42984618454.96
Hypothetical proteinSAMEA3649444_04033Not AvailablePositive4298687 - 42989328997.61
Hnh endonucleaseSAMEA3649444_04034Not AvailablePositive4298988 - 429932913182.9
Terminase small subunitSAMEA3649444_04035Not AvailablePositive4299512 - 429997616943.5
Terminase large subunit-like proteinSAMEA3649444_04036Not AvailablePositive4299930 - 430167264855.8
Portal proteinSAMEA3649444_04037Not AvailablePositive4301672 - 430297948713.2
Head maturation proteaseSAMEA3649444_04038Not AvailablePositive4302993 - 430384129428.1

Displaying genes 71 – 80 of 5035 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total