Klebsiella pneumoniae strain EuSCAPE_ES191

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES191 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. It typically exists in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating motility. This strain has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. This bacterium is notably associated with numerous health impacts, particularly in humans, where it is linked to serious conditions such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Other health effects include liver abscesses, meningitis, and sepsis, highlighting its significant pathogenicity. It can also affect a wide range of hosts, including various mammals, birds, amphibians, and plants, indicating its versatility in different environments. Klebsiella pneumoniae strain EuSCAPE_ES191 is characterized by having a single replicon and two membranes, typical of its classification within the Enterobacteriaceae family. Its free-living biotic relationship suggests a capacity to survive in diverse ecological niches, which may contribute to its role as an opportunistic pathogen in immunocompromised individuals. The ecological insight drawn from its wide host range and pathogenic potential underscores the importance of understanding Klebsiella pneumoniae in both clinical and environmental contexts, as its adaptability may influence the dynamics of microbial communities and the spread of antibiotic resistance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES191

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES191
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES191 genome assembly,

Gene Summary

Adenine Count

1278295 bp

Thymine Count

1282103 bp

Guanine Count

1664925 bp

Cytosine Count

1636666 bp

Genome Length

5861989 bp

Protein-coding Genes

5236 genes

Non-Coding Genes

143 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phage tail length tape-measure protein 1SAMEA3649507_03280Not AvailablePositive3470952 - 3474359121708.0
AttrNot AvailableNot AvailablePositive3474665 - 3474703Not Available
AttlNot AvailableNot AvailablePositive3662843 - 3662906Not Available
putative prophage gp int for integraseSAMEA3649507_03469Not AvailableNegative3663501 - 366452939596.8
uncharacterised proteinSAMEA3649507_03470Not AvailableNegative3664529 - 366528128298.5
uncharacterised proteinSAMEA3649507_03471Not AvailableNegative3665278 - 366559812854.5
repressor proteinSAMEA3649507_03472Not AvailableNegative3665631 - 366625123098.1
uncharacterised proteinSAMEA3649507_03473Not AvailablePositive3666352 - 36665738037.96
phage regulatory proteinSAMEA3649507_03474Not AvailablePositive3666604 - 366710718099.7
uncharacterised proteinSAMEA3649507_03475Not AvailablePositive3667117 - 36673448404.25

Displaying genes 71 – 80 of 5379 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total