Klebsiella pneumoniae strain EuSCAPE_ES187

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES187 is a Gram-negative, rod-shaped bacterium known for its role as a facultative anaerobe and chemoheterotroph. This organism exhibits a versatile cell arrangement, presenting in chains, pairs, and singles. It possesses flagella, contributing to its mobility and allowing it to thrive in various environments. The strain is mesophilic, with an optimal growth temperature of 37°C, and is associated with diverse habitats, primarily host-associated environments. It has been identified in multiple hosts, including Homo sapiens, Gallus gallus, Metazoa, Viridiplantae, Danio rerio, Ovis aries, Phasianidae, Sus scrofa, Aves, Canis lupus familiaris, Amphibia, and Equidae. This broad host range underlines its ecological adaptability and potential for cross-species transmission. Klebsiella pneumoniae strain EuSCAPE_ES187 is recognized for its pathogenicity in humans, causing a multitude of health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to cause severe infections, including neonatal sepsis and pyogenic liver abscesses, highlights its clinical significance and the need for vigilance in managing infections associated with this strain. The presence of this bacterium in various host species suggests a complex ecological relationship, where it can act as both a free-living organism and a pathogen. Understanding its interactions with different hosts is essential for developing effective strategies to combat the infections it causes, emphasizing the importance of monitoring this strain in clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES187

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES187
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES187 genome assembly,

Gene Summary

Adenine Count

1371159 bp

Thymine Count

1369627 bp

Guanine Count

1716799 bp

Cytosine Count

1725302 bp

Genome Length

6182887 bp

Protein-coding Genes

5416 genes

Non-Coding Genes

186 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
amidohydrolaseSAMEA3649503_01018Not AvailableNegative1076377 - 107808361857.6
tonb-dependent receptor yncdSAMEA3649503_01019Not AvailableNegative1078281 - 108038677097.7
putative receptorSAMEA3649503_01020Not AvailablePositive1080645 - 108170638299.6
outer membrane lipoproteinSAMEA3649503_01021Not AvailablePositive1081875 - 10820967872.46
l-asparagine permeaseSAMEA3649503_01022Not AvailableNegative1082147 - 108360152404.1
lysr family transcriptional regulatorSAMEA3649503_01023Not AvailableNegative1083791 - 108467832861.7
dna topology modulation proteinSAMEA3649503_01024Not AvailablePositive1084952 - 108550321644.8
luciferase family protein ytmoSAMEA3649503_01025Not AvailablePositive1085595 - 108660236407.3
n-acetyl-l,l-diaminopimelate deacetylaseSAMEA3649503_01026Not AvailablePositive1086592 - 108771340352.8
nitrilotriacetate monooxygenase component aSAMEA3649503_01027Not AvailablePositive1087738 - 108905148807.0

Displaying genes 1131 – 1140 of 5602 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total