Klebsiella pneumoniae strain EuSCAPE_GR077

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR077 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph. This strain is capable of existing in various arrangements, including chains, pairs, and singles. It possesses flagella, allowing for mobility, and has a mesophilic temperature range, with an optimal growth temperature of 37°C. This strain is primarily associated with hosts such as Homo sapiens, Gallus gallus, and various Metazoa, among others. It exhibits a free-living biotic relationship but is notably pathogenic to humans. Klebsiella pneumoniae strain EuSCAPE_GR077 is implicated in a wide range of health complications, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The extensive list of health effects indicates its significant role in both hospital-acquired and community-associated infections. With a single replicon and a double membrane structure, this strain reflects the typical characteristics of many Gram-negative bacteria. The pathogenicity of Klebsiella pneumoniae strains like EuSCAPE_GR077 highlights the importance of understanding their ecological roles and interactions within host organisms. Given its capacity to cause serious infections, monitoring and studying this strain are crucial for public health, especially in clinical settings where vulnerable populations are at risk. Its ability to thrive in diverse environments, including those associated with various hosts, may facilitate its persistence and spread within ecosystems, raising concerns for infection control and prevention strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR077

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR077
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR077


Gene Summary

Adenine Count

1274993 bp

Thymine Count

1274728 bp

Guanine Count

1668446 bp

Cytosine Count

1652441 bp

Genome Length

5870608 bp

Protein-coding Genes

5303 genes

Non-Coding Genes

395 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fes assembly protein iscxSAMEA3649696_00439Not AvailableNegative480913 - 4811137745.94
ferredoxinSAMEA3649696_00440Not AvailableNegative481115 - 48145012312.4
chaperone protein hscaSAMEA3649696_00441Not AvailableNegative481452 - 48330265399.2
chaperone protein hscbSAMEA3649696_00442Not AvailableNegative483318 - 48383319825.4
iron binding protein isca for iron-sulfur cluster assemblySAMEA3649696_00443Not AvailableNegative483908 - 48423111449.5
iron-sulfur cluster assembly scaffold protein iscuSAMEA3649696_00444Not AvailableNegative484249 - 48463513807.3
cysteine desulfuraseSAMEA3649696_00445Not AvailableNegative484662 - 48587645059.1
iron-sulfur cluster regulator iscrSAMEA3649696_00446Not AvailableNegative486055 - 48654617551.9
trna:cm32/um32 methyltransferaseSAMEA3649696_00447Not AvailableNegative486781 - 48751526799.4
inositol-1-monophosphataseSAMEA3649696_00448Not AvailablePositive487636 - 48843929322.0

Displaying genes 741 – 750 of 5698 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total