Klebsiella pneumoniae strain EuSCAPE_GR064

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR064 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. It is capable of existing in various arrangements, such as chains, pairs, and singles. This strain is characterized by its motility, attributed to the presence of flagella, and is classified as mesophilic, with an optimal growth temperature of 37°C. K. pneumoniae strain EuSCAPE_GR064 is primarily associated with hosts from diverse taxa, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae. Its pathogenic potential is significant, as it is known to cause a range of serious health complications in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is nonsporulating and possesses a single replicon and a double membrane structure, which is characteristic of Gram-negative bacteria. While it has a free-living biotic relationship, its presence in human-associated environments highlights its role as a pathogen. The ecological implications of K. pneumoniae strain EuSCAPE_GR064 are noteworthy, as its wide range of hosts and pathogenic effects underline the importance of understanding its transmission and resistance mechanisms. This knowledge is crucial for developing effective control measures to mitigate the risks associated with infections caused by this opportunistic pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR064

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR064
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR064 genome assembly,

Gene Summary

Adenine Count

1126630 bp

Thymine Count

1125228 bp

Guanine Count

1535385 bp

Cytosine Count

1511719 bp

Genome Length

5298962 bp

Protein-coding Genes

4847 genes

Non-Coding Genes

126 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
anti-rna polymerase sigma factor sigeSAMEA3649683_00015Not AvailablePositive15439 - 1608923985.4
anti-sigma e factorSAMEA3649683_00016Not AvailablePositive16089 - 1704535196.8
sigma factor rpoe regulatory protein rsecSAMEA3649683_00017Not AvailablePositive17042 - 1752116505.2
translation elongation factor lepaSAMEA3649683_00018Not AvailablePositive17707 - 1950666439.1
signal peptidase iSAMEA3649683_00019Not AvailablePositive19522 - 2049635791.3
ribonuclease iiiSAMEA3649683_00020Not AvailablePositive20746 - 2142625558.6
gtp-binding protein eraSAMEA3649683_00021Not AvailablePositive21423 - 2232833885.1
dna recombination and repair protein recoSAMEA3649683_00022Not AvailablePositive22340 - 2307727435.0
pyridoxine 5'-phosphate synthaseSAMEA3649683_00023Not AvailablePositive23089 - 2382026473.0
holo-[acyl-carrier protein] synthaseSAMEA3649683_00024Not AvailablePositive23820 - 2420014038.0

Displaying genes 71 – 80 of 4973 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total