Klebsiella pneumoniae strain EuSCAPE_GR064

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR064 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. It is capable of existing in various arrangements, such as chains, pairs, and singles. This strain is characterized by its motility, attributed to the presence of flagella, and is classified as mesophilic, with an optimal growth temperature of 37°C. K. pneumoniae strain EuSCAPE_GR064 is primarily associated with hosts from diverse taxa, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae. Its pathogenic potential is significant, as it is known to cause a range of serious health complications in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is nonsporulating and possesses a single replicon and a double membrane structure, which is characteristic of Gram-negative bacteria. While it has a free-living biotic relationship, its presence in human-associated environments highlights its role as a pathogen. The ecological implications of K. pneumoniae strain EuSCAPE_GR064 are noteworthy, as its wide range of hosts and pathogenic effects underline the importance of understanding its transmission and resistance mechanisms. This knowledge is crucial for developing effective control measures to mitigate the risks associated with infections caused by this opportunistic pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR064

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR064
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR064 genome assembly,

Gene Summary

Adenine Count

1126630 bp

Thymine Count

1125228 bp

Guanine Count

1535385 bp

Cytosine Count

1511719 bp

Genome Length

5298962 bp

Protein-coding Genes

4847 genes

Non-Coding Genes

126 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
mfs-type transporter protein ycadSAMEA3649683_03412Not AvailableNegative3637078 - 363822641635.6
anaerobic dimethyl sulfoxide reductase subunit cSAMEA3649683_03413Not AvailableNegative3638501 - 363936430978.4
na(+)citrate oh(-) antiporterSAMEA3649683_03414Not AvailableNegative3639694 - 364103447474.7
[citrate (pro-3s)-lyase] ligaseSAMEA3649683_03415Not AvailablePositive3641399 - 364231934132.4
citrate lyase subunit gammaSAMEA3649683_03416Not AvailablePositive3642350 - 364264310427.7
citrate lyase subunit betaSAMEA3649683_03417Not AvailablePositive3642640 - 364350931353.7
citrate lyase subunit alphaSAMEA3649683_03418Not AvailablePositive3643538 - 364504654001.7
triphosphoribosyl-dephospho-coa synthaseSAMEA3649683_03419Not AvailablePositive3645065 - 364597332647.5
dihydrodipicolinate reductaseSAMEA3649683_03420Not AvailablePositive3646202 - 364702328649.4
carbamoyl phosphate synthase small subunitSAMEA3649683_03421Not AvailablePositive3647481 - 364862941219.0

Displaying genes 3421 – 3430 of 4973 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total