Klebsiella pneumoniae strain EuSCAPE_GR071

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR071 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It exhibits a chemoheterotrophic metabolism and can be found in diverse habitats, particularly associated with hosts such as Homo sapiens and various animal species, including Gallus gallus and Sus scrofa. The strain is characterized by its ability to form chains, pairs, or singles, and possesses flagella, indicating motility. EuSCAPE_GR071 thrives optimally at 37°C, falling within a mesophilic temperature range. This strain has a simple genomic structure with one replicon and two membranes, typical of Gram-negative bacteria. It is free-living but demonstrates significant pathogenicity in humans, being associated with a range of infections, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The extensive list of health effects includes serious conditions like sepsis and neonatal sepsis, highlighting its clinical relevance. The presence of Klebsiella pneumoniae in such a wide array of hosts suggests an ecological versatility and adaptability, which may contribute to its role as an opportunistic pathogen. This adaptability can facilitate the transmission of virulence factors among host species, potentially leading to increased public health concerns, especially in hospital settings where infections can be severe and difficult to manage. Understanding the ecological relationships and pathogenic potential of strains like EuSCAPE_GR071 is critical for developing strategies to combat infections caused by this bacterium.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR071

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR071
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR071 genome assembly,

Gene Summary

Adenine Count

1221183 bp

Thymine Count

1218437 bp

Guanine Count

1604533 bp

Cytosine Count

1603087 bp

Genome Length

5647240 bp

Protein-coding Genes

5006 genes

Non-Coding Genes

377 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Gp21SAMEA3649690_01509Not AvailableNegative1546874 - 1558090397782.0
Tail assembly protein iSAMEA3649690_01510Not AvailableNegative1558153 - 155874620635.5
Minor tail proteinSAMEA3649690_01511Not AvailableNegative1559237 - 155994727623.7
Minor tail protein lSAMEA3649690_01512Not AvailableNegative1559949 - 156070428111.8
Minor tail protein mSAMEA3649690_01513Not AvailableNegative1560701 - 156103912777.0
Tail length tape measure proteinSAMEA3649690_01514Not AvailableNegative1561039 - 1564395118621.0
Putative tail assembly chaperoneSAMEA3649690_01515Not AvailableNegative1564628 - 156499313283.0
Major tail shaft subunitSAMEA3649690_01516Not AvailableNegative1565051 - 156551216040.3
Gp11SAMEA3649690_01517Not AvailableNegative1565544 - 156594514870.2
Gp10SAMEA3649690_01518Not AvailableNegative1565942 - 156633114729.9

Displaying genes 71 – 80 of 5383 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total