Klebsiella pneumoniae strain EuSCAPE_GR070

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR070 is a significant Gram-negative bacterium classified as a facultative anaerobe and a chemoheterotroph. This organism is rod-shaped and can be found in various arrangements, including chains, pairs, and singles. It possesses flagella, indicating its mobility, and thrives optimally at 37°C, fitting within a mesophilic temperature range. This strain is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, various Metazoa, Viridiplantae, Danio rerio, Ovis aries, Phasianidae, Sus scrofa, Aves, Canis lupus familiaris, Amphibia, and Equidae. Such a diverse host range suggests its ecological versatility and adaptation capabilities. Klebsiella pneumoniae strain EuSCAPE_GR070 is nonsporulating and has a biotic relationship categorized as free-living. With a single replicon and two membranes, it is well-structured for survival in various environments, including within its hosts. This bacterium is clinically significant, being associated with numerous health effects, primarily in humans. It is known to cause conditions such as bacteremia, urinary tract infections, pneumonia, and various abdominal infections, among others. The presence of this strain in both clinical and environmental contexts underscores its pathogenic potential, which is indicative of its role in human health and disease dynamics. The ability of Klebsiella pneumoniae strain EuSCAPE_GR070 to inhabit diverse environments and hosts while causing a range of diseases highlights its ecological and clinical importance. Its versatility may contribute to its persistence in various settings, emphasizing the need for ongoing monitoring and research.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR070

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR070
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR070 genome assembly,

Gene Summary

Adenine Count

1115938 bp

Thymine Count

1112549 bp

Guanine Count

1506112 bp

Cytosine Count

1508057 bp

Genome Length

5242656 bp

Protein-coding Genes

4723 genes

Non-Coding Genes

225 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
4-hydroxy-3-methylbut-2-enyl diphosphate reductaseSAMEA3649689_03733Not AvailableNegative3980043 - 398099334449.1
fkbp-type peptidyl-prolyl cis-trans isomeraseSAMEA3649689_03734Not AvailableNegative3980995 - 398144416156.0
lipoprotein signal peptidaseSAMEA3649689_03735Not AvailableNegative3981560 - 398206018326.6
isoleucyl-trna synthetaseSAMEA3649689_03736Not AvailableNegative3982060 - 3984912105863.0
bifunctional riboflavin kinase/fmn adenylyltransferaseSAMEA3649689_03737Not AvailableNegative3984920 - 398585834373.8
uncharacterised proteinSAMEA3649689_03738Not AvailableNegative3986203 - 39864127783.35
lysr family transcriptional regulatorSAMEA3649689_03739Not AvailableNegative3986571 - 398746734036.1
na+/h+ antiporter nhaa typeSAMEA3649689_03740Not AvailableNegative3987522 - 398874543277.9
chaperone protein dnajSAMEA3649689_03741Not AvailableNegative3988875 - 399000841012.7
chaperone protein dnakSAMEA3649689_03742Not AvailableNegative3990096 - 399201269112.7

Displaying genes 3791 – 3800 of 4948 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total