Klebsiella pneumoniae strain EuSCAPE_GR053

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR053 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain typically forms chains, pairs, or single cells and possesses flagella, which contribute to its mobility. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. This bacterium is primarily host-associated, free-living in various environments, and has been identified in multiple hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), and a variety of other species across the Metazoa, Viridiplantae, and aquatic organisms like Danio rerio (zebrafish). Klebsiella pneumoniae strain EuSCAPE_GR053 is known for its significant pathogenicity in humans, being associated with numerous health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis. It can also cause infections in other hosts, affecting both mammals and birds, indicating its broad ecological niche. The presence of this strain in diverse hosts underscores its adaptability and potential for zoonotic transmission, reflecting its ecological versatility. The strain's ability to thrive in various biological environments may facilitate its role in disease dynamics, especially in clinical settings where it contributes to a range of severe infections. Understanding the pathogenicity and ecological interactions of Klebsiella pneumoniae strain EuSCAPE_GR053 is crucial for developing strategies to manage and prevent infections it may cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR053

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR053
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR053 genome assembly,

Gene Summary

Adenine Count

1218125 bp

Thymine Count

1223789 bp

Guanine Count

1631014 bp

Cytosine Count

1618315 bp

Genome Length

5691243 bp

Protein-coding Genes

5179 genes

Non-Coding Genes

303 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Ead-like proteinSAMEA3649672_01423Not AvailableNegative1483691 - 148453331249.5
Hypothetical proteinSAMEA3649672_01424Not AvailableNegative1484530 - 14846434056.57
Hypothetical proteinSAMEA3649672_01425Not AvailableNegative1484640 - 148514618114.8
Exclusion proteinSAMEA3649672_01426Not AvailableNegative1485143 - 148543610648.8
Gene p proteinSAMEA3649672_01427Not AvailableNegative1485436 - 148686653750.3
Replication proteinSAMEA3649672_01428Not AvailableNegative1486856 - 148775534093.5
uncharacterised proteinSAMEA3649672_01429Not AvailableNegative1487748 - 14878945776.07
Cii proteinSAMEA3649672_01430Not AvailableNegative1487980 - 14882018110.72
Helix-turn-helix domain-containing proteinSAMEA3649672_01431Not AvailableNegative1488242 - 14884758286.01
CiSAMEA3649672_01432Not AvailablePositive1488603 - 148929225443.4

Displaying genes 81 – 90 of 5482 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total