Klebsiella pneumoniae strain EuSCAPE_ES265

Klebsiella pneumoniae strain EuSCAPE_ES265 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is notable for its mobility and the presence of flagella, allowing it to navigate its habitat, which is primarily host-associated. The optimal growth temperature for this mesophilic organism is 37°C. K. pneumoniae strain EuSCAPE_ES265 can exist in various cellular arrangements, including chains, pairs, and singles, contributing to its adaptability in different environments. It has a biotic relationship classified as free-living, indicating its ability to survive independently while also being associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoan species, including mammals and amphibians. The strain is implicated in a multitude of health issues, particularly in humans, where it can cause conditions such as bacteremia, urinary tract infections, pneumonia, and more severe complications such as meningitis and sepsis. These health effects reflect its pathogenicity, particularly in immunocompromised individuals. The presence of a single replicon and a double membrane structure aligns with the typical characteristics of gram-negative bacteria, which are known to exhibit complex interactions with their environments and hosts. The diverse range of potential hosts and associated health impacts underscores the ecological significance of K. pneumoniae strain EuSCAPE_ES265, highlighting its role as both a commensal and a pathogen in various biological contexts.