Klebsiella pneumoniae strain EuSCAPE_GR027

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR027 is a Gram-negative, rod-shaped bacterium that exhibits a diverse range of pathogenic effects in humans and various animal hosts. This strain is identified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments, and is classified as a chemoheterotroph, utilizing organic compounds for energy. The bacterium typically arranges itself in chains, pairs, and singles, and possesses flagella, which contribute to its mobility. Its optimal growth temperature is 37°C, situating it within the mesophilic temperature range. K. pneumoniae strain EuSCAPE_GR027 is nonsporulating and has a single replicon with a double membrane structure, characteristic of Gram-negative organisms. This strain is associated with a wide array of biotic relationships, being free-living yet also a significant pathogen, particularly in humans (Homo sapiens). It is linked to various health concerns, including bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. The broad host range extends to species across Metazoa, Viridiplantae, and several animals including birds, mammals, and fish, indicating its ecological adaptability. The ability to cause infections in a diverse range of hosts underscores K. pneumoniae strain EuSCAPE_GR027's importance in both clinical settings and ecological contexts, highlighting its role in microbial pathogenicity and the potential for zoonotic transmission. The strain's versatility as a pathogen emphasizes the need for ongoing surveillance and research into its mechanisms of infection and resistance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR027

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR027
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR027 genome assembly,

Gene Summary

Adenine Count

1221030 bp

Thymine Count

1218663 bp

Guanine Count

1606746 bp

Cytosine Count

1638213 bp

Genome Length

5684652 bp

Protein-coding Genes

5179 genes

Non-Coding Genes

251 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive473911 - 473922Not Available
IntegraseSAMEA3649640_00418Not AvailablePositive475145 - 47637146700.5
uncharacterised proteinSAMEA3649640_00419Not AvailablePositive476464 - 47740536075.8
Transcriptional regulatorSAMEA3649640_00420Not AvailablePositive477587 - 47787111198.2
RoiSAMEA3649640_00421Not AvailablePositive477882 - 47866128437.3
uncharacterised proteinSAMEA3649640_00422Not AvailablePositive478645 - 47938227327.9
uncharacterised proteinSAMEA3649640_00423Not AvailablePositive479375 - 4795637224.61
uncharacterised proteinSAMEA3649640_00424Not AvailablePositive479556 - 47987011508.2
uncharacterised proteinSAMEA3649640_00425Not AvailablePositive479867 - 48023513535.6
uncharacterised proteinSAMEA3649640_00426Not AvailablePositive480232 - 48059713986.0

Displaying genes 1 – 10 of 5430 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total