Klebsiella pneumoniae strain EuSCAPE_GR030

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR030 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. It is capable of existing in various arrangements, including chains, pairs, and singles, and exhibits mobility due to the presence of flagella. This strain thrives optimally at 37°C and falls within the mesophilic temperature range. The bacterium is associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. It plays a role in several biotic relationships, primarily as a free-living organism. However, Klebsiella pneumoniae strain EuSCAPE_GR030 is notably pathogenic to humans, leading to a wide array of health effects. These include bacteremia, urinary tract infections, pneumonia, sepsis, and several other severe infections such as liver abscesses and neonatal sepsis. With a single replicon and two membranes, this strain’s structural composition supports its adaptability in various environments, including human hosts. The extensive list of health effects linked to this bacterium underscores its significant role in both clinical and ecological contexts. Its presence in multiple host species emphasizes the potential for zoonotic transmission and highlights the ecological interconnectedness of pathogens. Understanding the traits of Klebsiella pneumoniae strain EuSCAPE_GR030 can inform public health strategies aimed at managing infections and mitigating the risks associated with this opportunistic pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR030

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR030
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR030 genome assembly,

Gene Summary

Adenine Count

1225978 bp

Thymine Count

1228554 bp

Guanine Count

1640496 bp

Cytosine Count

1619699 bp

Genome Length

5714727 bp

Protein-coding Genes

5167 genes

Non-Coding Genes

341 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Protein of unknown function duf927SAMEA3649646_01345Not AvailablePositive1443613 - 144574877917.0
uncharacterised proteinSAMEA3649646_01346Not AvailablePositive1446091 - 144642612245.2
uncharacterised proteinSAMEA3649646_01347Not AvailableNegative1446475 - 144698718229.7
Phage major capsid proteinSAMEA3649646_01348Not AvailablePositive1447251 - 144841742984.8
Putative prohead proteaseSAMEA3649646_01349Not AvailablePositive1448469 - 144902920928.6
Portal proteinSAMEA3649646_01350Not AvailablePositive1449031 - 145027246391.8
Head-tail connector iiSAMEA3649646_01351Not AvailablePositive1450269 - 145060412410.9
Head-tail connector proteinSAMEA3649646_01352Not AvailablePositive1450601 - 145090011214.5
Hypothetical proteinSAMEA3649646_01353Not AvailablePositive1450900 - 145134317586.8
uncharacterised proteinSAMEA3649646_01354Not AvailablePositive1451336 - 14514886277.46

Displaying genes 11 – 20 of 5508 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total