Klebsiella pneumoniae strain 4300STDY6470419

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 4300STDY6470419 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophy as its energy source. It typically arranges itself in chains, pairs, or singles and possesses flagella, allowing for mobility. The strain is mesophilic, with an optimal growth temperature of 37°C, and has a single replicon and two membranes. This organism is notably free-living but is also associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans, as well as Viridiplantae and Danio rerio. Its pathogenicity is significant in humans, where it causes a variety of health effects such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is implicated in both community-acquired and nosocomial infections, affecting multiple systems including the urinary tract, liver, and respiratory system. Given its ability to thrive in diverse environments and its association with numerous hosts, Klebsiella pneumoniae strain 4300STDY6470419 exemplifies the complexities of microbial interactions within ecosystems. Its pathogenic potential highlights the importance of understanding such bacteria in order to manage and prevent infections in both human and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 4300STDY6470419

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 4300STDY6470419
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 4300STDY6470419 genome assembly,

Gene Summary

Adenine Count

1370990 bp

Thymine Count

1367023 bp

Guanine Count

1746823 bp

Cytosine Count

1790674 bp

Genome Length

6285981 bp

Protein-coding Genes

5745 genes

Non-Coding Genes

124 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
laci family transcriptional regulatorSAMEA4364600_04256Not AvailablePositive4477510 - 447852336738.7
inositol monophosphataseSAMEA4364600_04257Not AvailablePositive4478534 - 447929527379.5
anti-adapter protein iramSAMEA4364600_04258Not AvailableNegative4479334 - 447968713774.6
outer membrane protein assembly factor yaetSAMEA4364600_04259Not AvailableNegative4480239 - 448266289007.9
hydrolaseSAMEA4364600_04260Not AvailablePositive4483288 - 448504863570.8
arac family transcriptional regulatorSAMEA4364600_04261Not AvailablePositive4485082 - 448545014552.8
tonb-dependent receptorSAMEA4364600_04262Not AvailableNegative4485714 - 448797282744.8
putative periplasmic binding protein of transport systemSAMEA4364600_04263Not AvailablePositive4488560 - 449014059104.5
ssdna-binding proteinSAMEA4364600_04264Not AvailableNegative4490265 - 449078918712.8
excinuclease abc subunit aSAMEA4364600_04265Not AvailablePositive4491041 - 4493866103980.0

Displaying genes 4171 – 4180 of 5869 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total