Klebsiella pneumoniae strain 4300STDY6636980

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 4300STDY6636980 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain typically resides in a host-associated habitat, demonstrating its ability to form chains, pairs, and singles. It possesses flagella, indicating mobility, and thrives optimally at a temperature of 37°C, categorizing it as mesophilic. The biotic relationships of this bacterium are notable; it is considered free-living, yet it has a wide range of hosts, including Homo sapiens, various avian species (Gallus gallus, Phasianidae, Aves), mammals (Sus scrofa, Canis lupus familiaris, Equidae), amphibians, and fish (Danio rerio). This diverse host range points to the bacterium's adaptability and potential for cross-species transmission. Klebsiella pneumoniae strain 4300STDY6636980 is associated with several significant health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity is primarily directed towards human hosts, where it can cause serious infections such as pyogenic liver abscesses and neonatal sepsis. Given its capacity for causing a wide variety of infections and its presence in multiple hosts, Klebsiella pneumoniae strain 4300STDY6636980 underscores the importance of monitoring this bacterium in clinical settings and its ecological interactions. Understanding its pathogenic mechanisms and host relationships can contribute to better management strategies for infections it may cause, particularly in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 4300STDY6636980

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 4300STDY6636980
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 4300STDY6636980 genome assembly,

Gene Summary

Adenine Count

1216272 bp

Thymine Count

1217018 bp

Guanine Count

1613629 bp

Cytosine Count

1619938 bp

Genome Length

5667435 bp

Protein-coding Genes

5104 genes

Non-Coding Genes

205 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
NineSAMEA24018418_01675Not AvailablePositive1798788 - 17989586687.45
Putative recombination endonucleaseSAMEA24018418_01676Not AvailablePositive1798951 - 179953223019.4
NinySAMEA24018418_01677Not AvailablePositive1799529 - 17997538598.38
Conserved hypothetical bacteriophage proteinSAMEA24018418_01678Not AvailablePositive1799750 - 17998905674.0
Bacteriophage antiterminator protein qSAMEA24018418_01679Not AvailablePositive1799887 - 180057626115.0
Trna,type:met,anti_codon:cat;Not AvailableNot AvailablePositive1800779 - 1800856Not Available
Trna,type:arg,anti_codon:tct;Not AvailableNot AvailablePositive1800862 - 1800938Not Available
Hypothetical proteinSAMEA24018418_01682Not AvailablePositive1801208 - 180152211786.1
LysinSAMEA24018418_01683Not AvailablePositive1801525 - 180202818416.3
Putative rz1 lytic proteinSAMEA24018418_01684Not AvailablePositive1802233 - 180255011692.4

Displaying genes 31 – 40 of 5309 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total