Escherichia coli strain VREC0288

Escherichia coli strain VREC0288 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is typically found in a host-associated habitat and is mesophilic, with an optimal growth temperature of 37°C. It possesses a unique cellular organization, appearing in pairs and singles, and has a single replicon and a double membrane structure. VREC0288 has a diverse range of hosts, including Homo sapiens, various livestock such as Gallus gallus and Bos taurus, and other species across multiple taxonomic groups such as Metazoa, Aves, and Mammalia. This broad host range highlights its ecological versatility and ability to adapt to different biological environments. The strain is associated with numerous health effects, particularly in humans, where it is linked to urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as septicemia and hemolytic uremic syndrome (HUS). Additionally, it can cause neonatal meningitis and contribute to various forms of colibacillosis and gastrointestinal diseases in other hosts. Given its pathogenicity, particularly in human health, E. coli strain VREC0288 serves as an important model for understanding enteric pathogens and their impact on both animal and human health. Its ability to thrive in multiple hosts emphasizes the interconnectedness of host-pathogen dynamics and the potential for zoonotic transmission of infections.