Actinobacillus pleuropneumoniae strain NCTC11407

Actinobacillus pleuropneumoniae strain NCTC11407 is a Gram-negative bacterium recognized for its pathogenicity in various hosts, particularly in pigs (Sus scrofa). This microbe is facultatively anaerobic, thriving optimally at a temperature of 37°C, which falls within the mesophilic range. Its cellular arrangement can be observed in chains, pairs, or singles, and it has a rod shape. Notably, A. pleuropneumoniae lacks mobility, despite possessing flagella, which may play a role in its biological processes. The bacterium is characterized by having two membranes and a single replicon. It exhibits a symbiotic relationship with its hosts, which include not only swine but also Bos (cattle), Metazoa, Equus caballus (horses), and members of the Equidae family. A. pleuropneumoniae is associated with a range of health effects, primarily in pigs, leading to serious conditions such as porcine pleuropneumonia, septicemia, and several other infections including endocarditis, peritonitis, meningitis, arthritis, mastitis, metritis, and even stillbirth. Understanding the ecological role and health impacts of A. pleuropneumoniae is crucial, particularly given its significance in veterinary microbiology. The bacterium's ability to establish itself within diverse host species and its association with severe health issues highlights the necessity for ongoing research and monitoring to mitigate its impact on livestock health and productivity. This underscores the intricate relationships between microbial pathogens and their hosts in agricultural ecosystems.