Kocuria rosea strain NCTC7528

Coccusaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Micrococcales

Family

Micrococcaceae

Genus

Kocuria

Description

Kocuria rosea strain NCTC7528 is a Gram-positive, aerobic coccus characterized by its arrangement in pairs and presence of flagella. This bacterium has been isolated from various habitats, including indoor dust, Iranian hot springs, and skin. Its adaptability to diverse environments highlights its ecological versatility. Kocuria rosea is known to infect Homo sapiens, particularly in cases involving individuals with underlying co-morbidities. The bacterium has been implicated in several significant health issues, including endocarditis, peritonitis, central line-associated bloodstream infections, and brain abscesses. Other serious conditions associated with this strain include meningitis, bacteremia/sepsis, and acute cholecystitis. These associations suggest that Kocuria rosea can be a noteworthy opportunistic pathogen in clinical settings, especially in nosocomial infections. The presence of just one replicon in Kocuria rosea may contribute to its genetic stability, which can play a role in its pathogenicity and resistance mechanisms. The bacterium's prevalence in indoor dust indicates potential routes of transmission, emphasizing the importance of maintaining hygiene in environments where vulnerable populations may reside. Understanding the ecological niches occupied by Kocuria rosea can provide insights into its transmission dynamics and potential impact on public health, particularly in healthcare facilities.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMicrococcales
FamilyMicrococcaceae
GenusKocuria
SpeciesKocuria rosea
Strainstrain NCTC7528

Profile

Physiology
Gram staining propertiesPositive
ShapeCoccus
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Kocuria rosea strain NCTC7528
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsaerobic
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatdust; indoor dust; Iranian Ab-e-Siah hot springs; Iranian hot spring; skin
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementPairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Kocuria rosea strain NCTC7528 genome assembly, contig:

Gene Summary

Adenine Count

538180 bp

Thymine Count

540001 bp

Guanine Count

1433034 bp

Cytosine Count

1425717 bp

Genome Length

3936932 bp

Protein-coding Genes

3525 genes

Non-Coding Genes

73 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterized hth-type transcriptional regulator rv1985c/mt2039NCTC7528_03009Not AvailablePositive3251875 - 325276231961.9
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)NCTC7528_03010Not AvailableNegative3252782 - 325373234144.6
manganese-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenaseNCTC7528_03011Not AvailableNegative3253736 - 325480939549.1
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenaseNCTC7528_03012Not AvailablePositive3255018 - 325582727060.4
nodulation protein d 2NCTC7528_03013Not AvailableNegative3255885 - 325683534448.7
ureidoglycolate lyaseNCTC7528_03014Not AvailableNegative3256864 - 325787735916.4
predicted metal-dependent hydrolase of the tim-barrel foldNCTC7528_03015Not AvailableNegative3257888 - 325891936668.7
3-hydroxybenzoate 6-hydroxylase 1NCTC7528_03016Not AvailableNegative3258931 - 326005539702.4
putative cyclaseNCTC7528_03017Not AvailableNegative3260108 - 326108534855.7
bacillibactin exporterNCTC7528_03018Not AvailablePositive3261507 - 326271240589.7

Displaying genes 2991 – 3000 of 3598 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Nosocomial infectionCausesPMC10071551
Central line-associated bloodstream infectionsCausesPMC10071551
Infection in patients with underlying co-morbiditiesCausesPMC10071551
PeritonitisCausesPMC10071551
Brain abscessesCausesPMC10071551
MeningitisCausesPMC10071551
EndocarditisCausesPMC10071551
Bacteremia/ sepsisCausesPMC10071551
Acute cholecystitisCausesPMC10071551

Displaying health effects 1 – 9 of 9 in total