Klebsiella pneumoniae strain NCTC9617

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain NCTC9617 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This organism demonstrates mobility, facilitated by the presence of flagella, and typically exists in various arrangements, including chains, pairs, and singles. The strain thrives optimally at a temperature of 37°C, placing it within the mesophilic range. As a host-associated bacterium, K. pneumoniae NCTC9617 has been identified in multiple hosts, including Homo sapiens, various avian species (Phasianidae, Gallus gallus), mammals (Canis lupus familiaris, Sus scrofa, Ovis aries, Equidae), and aquatic organisms (Danio rerio, Amphibia). This broad host range indicates its ecological adaptability. Clinically, K. pneumoniae NCTC9617 is significant due to its association with a variety of health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is known for causing both community-acquired and healthcare-associated infections. Its pathogenic abilities highlight its role as a human pathogen, leading to severe health complications when it infects susceptible individuals. The ecological insight derived from the diverse hosts and pathogenic capabilities of K. pneumoniae NCTC9617 suggests that it can thrive in varied environments, potentially contributing to its persistence in both natural and clinical settings. Its ability to cause a wide range of infections underscores the importance of monitoring and understanding this bacterium within microbial populations and public health contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain NCTC9617

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain NCTC9617
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain NCTC9617 genome assembly, contig:

Gene Summary

Adenine Count

1194035 bp

Thymine Count

1197778 bp

Guanine Count

1589591 bp

Cytosine Count

1572742 bp

Genome Length

5554146 bp

Protein-coding Genes

6806 genes

Non-Coding Genes

504 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
monofunctional biosynthetic peptidoglycan transglycosylaseNCTC9617_04565Not AvailablePositive3393917 - 339464227081.0
phosphocarrier proteinNCTC9617_04566Not AvailableNegative3394706 - 33949789807.75
p-loop-containing kinaseNCTC9617_04567Not AvailableNegative3394975 - 339582932543.2
pts system transporter subunit iia-like nitrogen-regulatory protein ptsnNCTC9617_04568Not AvailableNegative3395875 - 339636317705.3
ribosome hibernation protein yhbhNCTC9617_04569Not AvailableNegative3396434 - 339672110760.0
rna polymerase sigma-54 factor rponNCTC9617_04570Not AvailableNegative3396744 - 339817753943.9
lipopolysaccharide abc transporterNCTC9617_04571Not AvailableNegative3398225 - 339895026844.4
lpta, protein essential for lps transport across the periplasmNCTC9617_04572Not AvailableNegative3398957 - 339950219863.8
lipopolysaccharide exporter periplasmic proteinNCTC9617_04573Not AvailableNegative3399471 - 340004621662.7
3-deoxy-d-manno-octulosonate 8-phosphate phosphataseNCTC9617_04574Not AvailableNegative3400043 - 34002135871.2

Displaying genes 4851 – 4860 of 7310 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total