Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This organism typically resides in host-associated environments and exhibits a chemoheterotrophic mode of energy acquisition, utilizing organic compounds for growth. The cells of this strain can be found in various arrangements, including singles, pairs, and chains, and they possess flagella, which contributes to their mobility. K. pneumoniae NCTC9504 thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. The bacterium has a simple genomic structure, characterized by a single replicon and the presence of two membranes. It is nonsporulating, which indicates that it does not form spores as a means of survival under adverse conditions. This strain is particularly notable for its association with health effects, specifically pneumonia, including community-acquired pneumonia (CAP). As a free-living organism, K. pneumoniae subsp. pneumoniae plays a significant role in human health, being a common pathogen that can lead to serious respiratory infections. Understanding the traits of this strain enhances our knowledge of its ecological niche and its impact on public health, particularly in the context of infections that arise in community settings. The strain's adaptability to different environments underscores the importance of monitoring such pathogens in clinical and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain NCTC9504

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 genome

Gene Summary

Adenine Count

1189535 bp

Thymine Count

1187383 bp

Guanine Count

1590237 bp

Cytosine Count

1588326 bp

Genome Length

5555481 bp

Protein-coding Genes

6040 genes

Non-Coding Genes

412 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
membrane alanine aminopeptidase nNCTC9504_04336Not AvailableNegative3616392 - 361697321099.8
nicotinate phosphoribosyltransferaseNCTC9504_04337Not AvailablePositive3617264 - 361832540874.6
nicotinate phosphoribosyltransferaseNCTC9504_04338Not AvailablePositive3618361 - 36185015024.25
n-acyl-l-amino acid amidohydrolaseNCTC9504_04339Not AvailableNegative3618544 - 361971042526.9
beta-ureidopropionaseNCTC9504_04340Not AvailableNegative3619729 - 362096744038.9
serine transporterNCTC9504_04341Not AvailableNegative3621039 - 362228045427.9
diaminopropionate ammonia-lyaseNCTC9504_04342Not AvailableNegative3622403 - 362361444064.8
leucine-responsive regulatory proteinNCTC9504_04343Not AvailablePositive3623923 - 362438717584.4
asparaginyl-trna synthetaseNCTC9504_04344Not AvailablePositive3624562 - 362562939978.1
asparaginyl-trna synthetaseNCTC9504_04345Not AvailablePositive3625626 - 362596112745.3

Displaying genes 4281 – 4290 of 6452 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total