Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This organism typically resides in host-associated environments and exhibits a chemoheterotrophic mode of energy acquisition, utilizing organic compounds for growth. The cells of this strain can be found in various arrangements, including singles, pairs, and chains, and they possess flagella, which contributes to their mobility. K. pneumoniae NCTC9504 thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. The bacterium has a simple genomic structure, characterized by a single replicon and the presence of two membranes. It is nonsporulating, which indicates that it does not form spores as a means of survival under adverse conditions. This strain is particularly notable for its association with health effects, specifically pneumonia, including community-acquired pneumonia (CAP). As a free-living organism, K. pneumoniae subsp. pneumoniae plays a significant role in human health, being a common pathogen that can lead to serious respiratory infections. Understanding the traits of this strain enhances our knowledge of its ecological niche and its impact on public health, particularly in the context of infections that arise in community settings. The strain's adaptability to different environments underscores the importance of monitoring such pathogens in clinical and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain NCTC9504

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 genome

Gene Summary

Adenine Count

1189535 bp

Thymine Count

1187383 bp

Guanine Count

1590237 bp

Cytosine Count

1588326 bp

Genome Length

5555481 bp

Protein-coding Genes

6040 genes

Non-Coding Genes

412 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lactoylglutathione lyaseNCTC9504_03072Not AvailableNegative2558942 - 25590975979.24
transcriptional regulators of sugar metabolismNCTC9504_03073Not AvailablePositive2559189 - 255995927603.4
amino acid exporterNCTC9504_03074Not AvailableNegative2559964 - 256059322508.4
carbonic anhydraseNCTC9504_03075Not AvailablePositive2560842 - 256147723245.8
protein of uncharacterised function (duf1471)NCTC9504_03076Not AvailableNegative2561790 - 25619997256.63
response regulator receiver proteinNCTC9504_03077Not AvailableNegative2562084 - 256280027520.5
cadc family transcriptional regulatorNCTC9504_03078Not AvailableNegative2562846 - 256328016724.6
uncharacterised proteinNCTC9504_03079Not AvailablePositive2563682 - 25638315537.78
beta-lactamaseNCTC9504_03080Not AvailableNegative2563919 - 256475529401.0
ribosomal protein s4NCTC9504_03081Not AvailableNegative2564763 - 256527819048.4

Displaying genes 3081 – 3090 of 6452 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total