Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This organism typically resides in host-associated environments and exhibits a chemoheterotrophic mode of energy acquisition, utilizing organic compounds for growth. The cells of this strain can be found in various arrangements, including singles, pairs, and chains, and they possess flagella, which contributes to their mobility. K. pneumoniae NCTC9504 thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. The bacterium has a simple genomic structure, characterized by a single replicon and the presence of two membranes. It is nonsporulating, which indicates that it does not form spores as a means of survival under adverse conditions. This strain is particularly notable for its association with health effects, specifically pneumonia, including community-acquired pneumonia (CAP). As a free-living organism, K. pneumoniae subsp. pneumoniae plays a significant role in human health, being a common pathogen that can lead to serious respiratory infections. Understanding the traits of this strain enhances our knowledge of its ecological niche and its impact on public health, particularly in the context of infections that arise in community settings. The strain's adaptability to different environments underscores the importance of monitoring such pathogens in clinical and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain NCTC9504

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 genome

Gene Summary

Adenine Count

1189535 bp

Thymine Count

1187383 bp

Guanine Count

1590237 bp

Cytosine Count

1588326 bp

Genome Length

5555481 bp

Protein-coding Genes

6040 genes

Non-Coding Genes

412 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nadh-ubiquinone oxidoreductase subunit mNCTC9504_02209Not AvailablePositive1821838 - 182336756472.0
nadh-ubiquinone oxidoreductase subunit nNCTC9504_02210Not AvailablePositive1823374 - 182483152124.5
ribonuclease zNCTC9504_02211Not AvailableNegative1824886 - 182580633473.2
elaa proteinNCTC9504_02212Not AvailablePositive1825864 - 182632517338.8
menaquinone-specific isochorismate synthaseNCTC9504_02213Not AvailablePositive1826461 - 182775047663.0
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthaseNCTC9504_02214Not AvailablePositive1827833 - 182813210478.7
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthaseNCTC9504_02215Not AvailablePositive1828138 - 182950249811.3
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthaseNCTC9504_02216Not AvailablePositive1829594 - 183025624134.6
naphthoate synthaseNCTC9504_02217Not AvailablePositive1830271 - 183112831626.8
o-succinylbenzoate-coa synthaseNCTC9504_02218Not AvailablePositive1831128 - 183209335254.6

Displaying genes 2281 – 2290 of 6452 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total