Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This organism typically resides in host-associated environments and exhibits a chemoheterotrophic mode of energy acquisition, utilizing organic compounds for growth. The cells of this strain can be found in various arrangements, including singles, pairs, and chains, and they possess flagella, which contributes to their mobility. K. pneumoniae NCTC9504 thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. The bacterium has a simple genomic structure, characterized by a single replicon and the presence of two membranes. It is nonsporulating, which indicates that it does not form spores as a means of survival under adverse conditions. This strain is particularly notable for its association with health effects, specifically pneumonia, including community-acquired pneumonia (CAP). As a free-living organism, K. pneumoniae subsp. pneumoniae plays a significant role in human health, being a common pathogen that can lead to serious respiratory infections. Understanding the traits of this strain enhances our knowledge of its ecological niche and its impact on public health, particularly in the context of infections that arise in community settings. The strain's adaptability to different environments underscores the importance of monitoring such pathogens in clinical and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain NCTC9504

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 genome

Gene Summary

Adenine Count

1189535 bp

Thymine Count

1187383 bp

Guanine Count

1590237 bp

Cytosine Count

1588326 bp

Genome Length

5555481 bp

Protein-coding Genes

6040 genes

Non-Coding Genes

412 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
esterase ypfhNCTC9504_02039Not AvailablePositive1680840 - 168153525137.9
inner membrane proteinNCTC9504_02040Not AvailableNegative1681584 - 16817878212.85
n-succinyl-l,l-diaminopimelate desuccinylaseNCTC9504_02041Not AvailableNegative1681814 - 168256027447.9
n-succinyl-l,l-diaminopimelate desuccinylaseNCTC9504_02042Not AvailableNegative1682547 - 16826453471.22
n-succinyl-l,l-diaminopimelate desuccinylaseNCTC9504_02043Not AvailableNegative1682642 - 168294110998.1
a glutathione-dependent thiol reductaseNCTC9504_02044Not AvailableNegative1682945 - 168329813477.3
aminoglycoside efflux pumpNCTC9504_02045Not AvailableNegative1683868 - 1686963111988.0
pyridine nucleotide-disulfide oxidoreductase family proteinNCTC9504_02046Not AvailablePositive1687336 - 168931871455.1
nudix hydrolase family protein yffhNCTC9504_02047Not AvailablePositive1689377 - 168997322158.3
protein of uncharacterised function (duf1176)NCTC9504_02048Not AvailablePositive1690037 - 169108338864.5

Displaying genes 2111 – 2120 of 6452 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total