Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This organism typically resides in host-associated environments and exhibits a chemoheterotrophic mode of energy acquisition, utilizing organic compounds for growth. The cells of this strain can be found in various arrangements, including singles, pairs, and chains, and they possess flagella, which contributes to their mobility. K. pneumoniae NCTC9504 thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. The bacterium has a simple genomic structure, characterized by a single replicon and the presence of two membranes. It is nonsporulating, which indicates that it does not form spores as a means of survival under adverse conditions. This strain is particularly notable for its association with health effects, specifically pneumonia, including community-acquired pneumonia (CAP). As a free-living organism, K. pneumoniae subsp. pneumoniae plays a significant role in human health, being a common pathogen that can lead to serious respiratory infections. Understanding the traits of this strain enhances our knowledge of its ecological niche and its impact on public health, particularly in the context of infections that arise in community settings. The strain's adaptability to different environments underscores the importance of monitoring such pathogens in clinical and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain NCTC9504

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain NCTC9504 genome

Gene Summary

Adenine Count

1189535 bp

Thymine Count

1187383 bp

Guanine Count

1590237 bp

Cytosine Count

1588326 bp

Genome Length

5555481 bp

Protein-coding Genes

6040 genes

Non-Coding Genes

412 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
anti-sigma e factorNCTC9504_01902Not AvailablePositive1561416 - 156237535521.1
sigma factor rpoe regulatory protein rsecNCTC9504_01903Not AvailablePositive1562368 - 15626409974.05
sigma factor rpoe regulatory protein rsecNCTC9504_01904Not AvailablePositive1562601 - 15628468473.61
translation elongation factor lepaNCTC9504_01905Not AvailablePositive1563032 - 156335511748.9
translation elongation factor lepaNCTC9504_01906Not AvailablePositive1563504 - 156482949175.8
signal peptidase iNCTC9504_01907Not AvailablePositive1564845 - 156581935791.3
gtp-binding protein eraNCTC9504_01909Not AvailablePositive1566746 - 156765133885.1
dna recombination and repair protein recoNCTC9504_01910Not AvailablePositive1567663 - 156840027435.0
pyridoxine 5'-phosphate synthaseNCTC9504_01911Not AvailablePositive1568412 - 156914326419.9
holo-[acyl-carrier protein] synthaseNCTC9504_01912Not AvailablePositive1569143 - 156952314038.0

Displaying genes 1981 – 1990 of 6452 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total