Klebsiella pneumoniae strain NCTC9637

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain NCTC9637 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, classifying it as a chemoheterotroph. This strain typically exists in host-associated habitats, displaying a diverse range of biotic relationships as a free-living organism. K. pneumoniae NCTC9637 is capable of mobility, attributed to the presence of flagella, and it typically forms chains, pairs, or single cells. The strain thrives optimally at 37°C, which is consistent with its mesophilic nature. It possesses a single replicon and is characterized by a double membrane structure. K. pneumoniae NCTC9637 has been identified as pathogenic to humans, contributing to a variety of health conditions such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. This strain's host range is extensive, affecting various species, including Homo sapiens, Gallus gallus, and numerous others across different taxa, including Metazoa and Viridiplantae. The bacterium's ability to infect diverse hosts highlights its ecological versatility and adaptability. Given its pathogenic potential and the wide range of infections it can cause, K. pneumoniae NCTC9637 represents a significant concern in clinical settings, particularly regarding the treatment of infections in immunocompromised individuals. Understanding the ecological and biological traits of this strain is crucial for developing effective strategies for infection prevention and control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain NCTC9637

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain NCTC9637
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain NCTC9637 genome assembly, contig:

Gene Summary

Adenine Count

1233269 bp

Thymine Count

1238766 bp

Guanine Count

1632753 bp

Cytosine Count

1636873 bp

Genome Length

5741661 bp

Protein-coding Genes

6330 genes

Non-Coding Genes

211 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nitrogen regulation protein nr(i)NCTC9637_06518Not AvailablePositive5628044 - 562886530989.2
coproporphyrinogen iii oxidaseNCTC9637_06519Not AvailableNegative5629122 - 562950514558.6
coproporphyrinogen iii oxidaseNCTC9637_06520Not AvailableNegative5629502 - 563049437924.2
gtpase activatorNCTC9637_06521Not AvailableNegative5630683 - 563118918780.9
gtp-binding protein engbNCTC9637_06524Not AvailablePositive5631773 - 563240523533.3
dna polymerase iNCTC9637_06526Not AvailableNegative5632754 - 563543299188.2
putative acyltransferaseNCTC9637_06527Not AvailablePositive5635944 - 563684334968.2
periplasmic thiol:disulfide interchange protein dsbaNCTC9637_06528Not AvailableNegative5636892 - 563751522946.6
yihe proteinNCTC9637_06529Not AvailableNegative5637543 - 563852938303.5
protein yihdNCTC9637_06530Not AvailableNegative5638605 - 563887410323.5

Displaying genes 6421 – 6430 of 6541 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total