Klebsiella pneumoniae strain NCTC9637

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain NCTC9637 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, classifying it as a chemoheterotroph. This strain typically exists in host-associated habitats, displaying a diverse range of biotic relationships as a free-living organism. K. pneumoniae NCTC9637 is capable of mobility, attributed to the presence of flagella, and it typically forms chains, pairs, or single cells. The strain thrives optimally at 37°C, which is consistent with its mesophilic nature. It possesses a single replicon and is characterized by a double membrane structure. K. pneumoniae NCTC9637 has been identified as pathogenic to humans, contributing to a variety of health conditions such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. This strain's host range is extensive, affecting various species, including Homo sapiens, Gallus gallus, and numerous others across different taxa, including Metazoa and Viridiplantae. The bacterium's ability to infect diverse hosts highlights its ecological versatility and adaptability. Given its pathogenic potential and the wide range of infections it can cause, K. pneumoniae NCTC9637 represents a significant concern in clinical settings, particularly regarding the treatment of infections in immunocompromised individuals. Understanding the ecological and biological traits of this strain is crucial for developing effective strategies for infection prevention and control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain NCTC9637

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain NCTC9637
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain NCTC9637 genome assembly, contig:

Gene Summary

Adenine Count

1233269 bp

Thymine Count

1238766 bp

Guanine Count

1632753 bp

Cytosine Count

1636873 bp

Genome Length

5741661 bp

Protein-coding Genes

6330 genes

Non-Coding Genes

211 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
queuosine biosynthesis protein quecNCTC9637_05192Not AvailablePositive4438724 - 443942525663.8
4-hydroxybenzoyl-coa thioesteraseNCTC9637_05193Not AvailableNegative4439537 - 443993815118.3
competence protein comeaNCTC9637_05194Not AvailableNegative4440050 - 444041812467.1
peptidyl-prolyl cis-trans isomerase dNCTC9637_05195Not AvailableNegative4440567 - 444244167839.4
dna-binding protein hu-betaNCTC9637_05196Not AvailableNegative4442656 - 44429289137.98
dna-binding atp-dependent protease laNCTC9637_05197Not AvailableNegative4443138 - 444535782267.0
atp-dependent clp protease atp-binding subunit clpxNCTC9637_05199Not AvailableNegative4445677 - 444695146296.6
atp-dependent clp protease proteolytic subunitNCTC9637_05200Not AvailableNegative4447202 - 444782523186.1
cell division trigger factorNCTC9637_05201Not AvailableNegative4448135 - 444943348115.3
cell division protein bolaNCTC9637_05202Not AvailableNegative4449779 - 445009311839.1

Displaying genes 5121 – 5130 of 6541 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total