Klebsiella variicola strain NCTC9177

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella variicola strain NCTC9177 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, allowing it to thrive in various oxygen conditions. This strain exhibits a unique cell arrangement, forming chains, pairs, and singles, and possesses flagella, which grants it mobility. It is classified as mesophilic, with an optimal growth temperature of 37°C, making it well-suited for growth within the human body and other warm-blooded hosts. Klebsiella variicola is known to engage in symbiotic relationships with various hosts, including Homo sapiens, Metazoa, Ovis aries, Aporrectodea sp., and Metaphire sieboldi. While it plays a role in the microbiome of these organisms, it is also associated with health concerns, particularly in causing bloodstream and urinary tract infections in humans. This strain has a single replicon and is nonsporulating, indicating a stable genetic structure without the formation of spores for survival under adverse conditions. The presence of two membranes is typical of Gram-negative bacteria, contributing to its structural characteristics and interactions with the environment. In summary, Klebsiella variicola strain NCTC9177 exemplifies a versatile bacterium that occupies a significant ecological niche, maintaining symbiotic relationships while also posing risks to human health. Its adaptability to varied hosts and environments underscores the complexity of microbial interactions within ecosystems and the potential consequences of dysbiosis.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella variicola
Strainstrain NCTC9177

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella variicola strain NCTC9177
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens, Metazoa, Ovis aries
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Klebsiella variicola strain NCTC9177 genome assembly, contig:

Gene Summary

Adenine Count

1255506 bp

Thymine Count

1253126 bp

Guanine Count

1666276 bp

Cytosine Count

1659259 bp

Genome Length

5834167 bp

Protein-coding Genes

7117 genes

Non-Coding Genes

271 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phenylacetate-coa oxygenase/reductase, paak subunitNCTC9177_04251Not AvailablePositive3326381 - 332695921504.8
phenylacetate degradation enoyl-coa hydratase paaaNCTC9177_04252Not AvailablePositive3327045 - 332821741540.7
enoyl-coa hydrataseNCTC9177_04253Not AvailablePositive3328220 - 332900828095.9
3-hydroxyacyl-coa dehydrogenaseNCTC9177_04254Not AvailablePositive3329012 - 333043351002.4
phenylacetic acid degradation protein paad, thioesteraseNCTC9177_04255Not AvailablePositive3330423 - 333084515178.2
acetyl-coa acetyltransferaseNCTC9177_04256Not AvailablePositive3330845 - 333205042085.8
phenylacetate-coenzyme a ligaseNCTC9177_04257Not AvailablePositive3332077 - 333339349026.9
phenylacetic acid degradation proteinNCTC9177_04258Not AvailablePositive3333484 - 333441934797.2
phenylacetic acid degradation protein paayNCTC9177_04259Not AvailablePositive3334429 - 333502521407.8
dna-binding proteinNCTC9177_04260Not AvailableNegative3335058 - 333534210361.3

Displaying genes 4251 – 4260 of 7388 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Bloodstream and urinary tract infectionsCausesPMC13366760

Displaying health effects 1 – 1 of 1 in total