Klebsiella variicola strain NCTC9177

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella variicola strain NCTC9177 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, allowing it to thrive in various oxygen conditions. This strain exhibits a unique cell arrangement, forming chains, pairs, and singles, and possesses flagella, which grants it mobility. It is classified as mesophilic, with an optimal growth temperature of 37°C, making it well-suited for growth within the human body and other warm-blooded hosts. Klebsiella variicola is known to engage in symbiotic relationships with various hosts, including Homo sapiens, Metazoa, Ovis aries, Aporrectodea sp., and Metaphire sieboldi. While it plays a role in the microbiome of these organisms, it is also associated with health concerns, particularly in causing bloodstream and urinary tract infections in humans. This strain has a single replicon and is nonsporulating, indicating a stable genetic structure without the formation of spores for survival under adverse conditions. The presence of two membranes is typical of Gram-negative bacteria, contributing to its structural characteristics and interactions with the environment. In summary, Klebsiella variicola strain NCTC9177 exemplifies a versatile bacterium that occupies a significant ecological niche, maintaining symbiotic relationships while also posing risks to human health. Its adaptability to varied hosts and environments underscores the complexity of microbial interactions within ecosystems and the potential consequences of dysbiosis.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella variicola
Strainstrain NCTC9177

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella variicola strain NCTC9177
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens, Metazoa, Ovis aries
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Klebsiella variicola strain NCTC9177 genome assembly, contig:

Gene Summary

Adenine Count

1255506 bp

Thymine Count

1253126 bp

Guanine Count

1666276 bp

Cytosine Count

1659259 bp

Genome Length

5834167 bp

Protein-coding Genes

7117 genes

Non-Coding Genes

271 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterized conserved small proteinNCTC9177_03685Not AvailableNegative2888374 - 28885356031.22
cyclic diguanylate phosphodiesteraseNCTC9177_03731Not AvailablePositive2931364 - 293184618618.7
isocitrate dehydrogenaseNCTC9177_03732Not AvailablePositive2932532 - 29326845528.78
uncharacterised proteinNCTC9177_03733Not AvailablePositive2933082 - 293342012653.3
uncharacterised proteinNCTC9177_03734Not AvailablePositive2933612 - 293389011091.8
arsr family transcriptional regulatorNCTC9177_03735Not AvailableNegative2934228 - 29343474326.25
arsr family transcriptional regulatorNCTC9177_03736Not AvailableNegative2934418 - 293481014518.6
act domain-containing proteinNCTC9177_03737Not AvailableNegative2934967 - 293547018371.3
antibiotic biosynthesis monooxygenaseNCTC9177_03738Not AvailableNegative2935467 - 29356436225.62
osmc family proteinNCTC9177_03739Not AvailableNegative2935970 - 293625110196.2

Displaying genes 3801 – 3810 of 7388 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Bloodstream and urinary tract infectionsCausesPMC13366760

Displaying health effects 1 – 1 of 1 in total