Klebsiella variicola strain NCTC9177

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella variicola strain NCTC9177 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, allowing it to thrive in various oxygen conditions. This strain exhibits a unique cell arrangement, forming chains, pairs, and singles, and possesses flagella, which grants it mobility. It is classified as mesophilic, with an optimal growth temperature of 37°C, making it well-suited for growth within the human body and other warm-blooded hosts. Klebsiella variicola is known to engage in symbiotic relationships with various hosts, including Homo sapiens, Metazoa, Ovis aries, Aporrectodea sp., and Metaphire sieboldi. While it plays a role in the microbiome of these organisms, it is also associated with health concerns, particularly in causing bloodstream and urinary tract infections in humans. This strain has a single replicon and is nonsporulating, indicating a stable genetic structure without the formation of spores for survival under adverse conditions. The presence of two membranes is typical of Gram-negative bacteria, contributing to its structural characteristics and interactions with the environment. In summary, Klebsiella variicola strain NCTC9177 exemplifies a versatile bacterium that occupies a significant ecological niche, maintaining symbiotic relationships while also posing risks to human health. Its adaptability to varied hosts and environments underscores the complexity of microbial interactions within ecosystems and the potential consequences of dysbiosis.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella variicola
Strainstrain NCTC9177

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella variicola strain NCTC9177
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens, Metazoa, Ovis aries
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Klebsiella variicola strain NCTC9177 genome assembly, contig:

Gene Summary

Adenine Count

1255506 bp

Thymine Count

1253126 bp

Guanine Count

1666276 bp

Cytosine Count

1659259 bp

Genome Length

5834167 bp

Protein-coding Genes

7117 genes

Non-Coding Genes

271 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
copper-sensing two-component system response regulator cpxrNCTC9177_01166Not AvailableNegative893283 - 89398126273.7
p pilus assembly/cpx signaling pathwayNCTC9177_01167Not AvailablePositive894131 - 89463418879.6
ferrous iron efflux protein fNCTC9177_01168Not AvailablePositive894793 - 89569532936.1
6-phosphofructokinaseNCTC9177_01169Not AvailablePositive895892 - 89685434986.4
ribonuclease e inhibitor rraaNCTC9177_01170Not AvailableNegative896916 - 89740117386.4
1,4-dihydroxy-2-naphthoate octaprenyltransferaseNCTC9177_01171Not AvailableNegative897494 - 89816824196.5
1,4-dihydroxy-2-naphthoate octaprenyltransferaseNCTC9177_01172Not AvailableNegative898153 - 8984139417.67
atp-dependent hsl protease atp-binding subunit hsluNCTC9177_01173Not AvailableNegative898483 - 89921427044.5
atp-dependent hsl protease atp-binding subunit hsluNCTC9177_01174Not AvailableNegative899174 - 89981824161.2
atp-dependent protease hslvNCTC9177_01175Not AvailableNegative899835 - 9000025996.16

Displaying genes 1321 – 1330 of 7388 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Bloodstream and urinary tract infectionsCausesPMC13366760

Displaying health effects 1 – 1 of 1 in total