Helicobacter pylori strain NCTC13094

Helicobacter pylori strain NCTC13094 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and the presence of flagella. This strain typically exists as single cells and is classified as mesophilic, with an optimal growth temperature of 37°C. It possesses a single replicon and is surrounded by two membranes, which is typical for Gram-negative bacteria. This strain is primarily host-associated, with a broad range of hosts including Homo sapiens, various birds such as Gallus gallus, and several mammalian groups including Primates, Mammalia, and Rodentia. H. pylori is noted for its pathogenicity in humans, where it is linked to numerous gastrointestinal diseases, including chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. The bacterium is also associated with conditions like gastroesophageal reflux disease (GERD) and functional dyspepsia. The ecological role of H. pylori extends beyond pathogenicity, as it is a free-living organism within its host's gastric environment. Its complex interactions with the host can lead to both symptomatic and asymptomatic responses. The presence of H. pylori in the gastrointestinal tract underscores its significance in human health, particularly regarding the development of chronic gastritis and peptic ulcer disease. Understanding the traits and impacts of H. pylori NCTC13094 can inform medical approaches to managing its associated diseases.