Hafnia alvei strain NCTC8535

Gram-negativeRodFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Hafniaceae

Genus

Hafnia

Description

Hafnia alvei strain NCTC8535 is a Gram-negative, rod-shaped bacterium that resides in hot spring habitats. This organism is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic conditions. The strain contains one replicon, contributing to its genetic stability and adaptability. Hafnia alvei is known to have a broad range of hosts, including Homo sapiens, Metazoa, Viridiplantae, Amphibia, Gastrotheca, Apis mellifera, and other Anthophila. This diverse host range suggests that H. alvei can interact with various biological systems, which may facilitate its ecological role in different environments. In terms of health effects, H. alvei is associated with septicemia, particularly in humans, as well as mild diseases. Notably, it has been implicated in septicemia in honeybees (Apis mellifera), which underscores its potential impact on both human and insect health. The genomic accessions for H. alvei strain NCTC8535 are cataloged under UGHO00000000.1, providing a resource for further study of its genetic makeup and pathogenic mechanisms. The strain's presence in varied hosts and its association with septicemia highlight its significance in microbiology, particularly regarding its role in disease dynamics within different ecosystems. Understanding the interactions between H. alvei and its hosts may provide insights into microbial ecology and the implications for health in both humans and insects.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyHafniaceae
GenusHafnia
SpeciesHafnia alvei
Strainstrain NCTC8535

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Hafnia alvei strain NCTC8535
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitathot spring
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Viridiplantae
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Hafnia alvei strain NCTC8535 genome assembly, contig:

Gene Summary

Adenine Count

1230251 bp

Thymine Count

1228315 bp

Guanine Count

1165036 bp

Cytosine Count

1166554 bp

Genome Length

4790156 bp

Protein-coding Genes

4107 genes

Non-Coding Genes

376 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aerobic glycerol-3-phosphate dehydrogenaseNCTC8535_03408Not AvailablePositive3549533 - 355101755945.5
maltodextrin phosphorylaseNCTC8535_03409Not AvailableNegative3551152 - 355359993356.0
glycogen synthaseNCTC8535_03410Not AvailableNegative3553694 - 355512452409.7
glucose-1-phosphate adenylyltransferaseNCTC8535_03411Not AvailableNegative3555202 - 355648548019.6
glycogen debranching enzymeNCTC8535_03412Not AvailableNegative3556549 - 355852874009.9
1,4-alpha-glucan branching enzyme glgbNCTC8535_03413Not AvailableNegative3558512 - 356074085259.3
4-alpha-glucanotransferaseNCTC8535_03414Not AvailableNegative3561084 - 356324681162.6
maltodextrin phosphorylaseNCTC8535_03415Not AvailableNegative3563258 - 356566691115.1
atp-dependent transcriptional activator maltNCTC8535_03416Not AvailablePositive3566230 - 3568944103897.0
inner membrane protein yaguNCTC8535_03417Not AvailableNegative3569012 - 356957521017.9

Displaying genes 3461 – 3470 of 4483 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

318 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da

Displaying 1–10 of 318 metabolites

Health Effects

Health ConditionRelationReference
Mild diseasesCausesPMC5615607
Bee septicemiaCausesPMC8729767
SepticemiaCausesPMC8729767

Displaying health effects 1 – 3 of 3 in total