Hafnia alvei strain NCTC8535

Gram-negativeRodFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Hafniaceae

Genus

Hafnia

Description

Hafnia alvei strain NCTC8535 is a Gram-negative, rod-shaped bacterium that resides in hot spring habitats. This organism is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic conditions. The strain contains one replicon, contributing to its genetic stability and adaptability. Hafnia alvei is known to have a broad range of hosts, including Homo sapiens, Metazoa, Viridiplantae, Amphibia, Gastrotheca, Apis mellifera, and other Anthophila. This diverse host range suggests that H. alvei can interact with various biological systems, which may facilitate its ecological role in different environments. In terms of health effects, H. alvei is associated with septicemia, particularly in humans, as well as mild diseases. Notably, it has been implicated in septicemia in honeybees (Apis mellifera), which underscores its potential impact on both human and insect health. The genomic accessions for H. alvei strain NCTC8535 are cataloged under UGHO00000000.1, providing a resource for further study of its genetic makeup and pathogenic mechanisms. The strain's presence in varied hosts and its association with septicemia highlight its significance in microbiology, particularly regarding its role in disease dynamics within different ecosystems. Understanding the interactions between H. alvei and its hosts may provide insights into microbial ecology and the implications for health in both humans and insects.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyHafniaceae
GenusHafnia
SpeciesHafnia alvei
Strainstrain NCTC8535

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Hafnia alvei strain NCTC8535
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitathot spring
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Viridiplantae
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Hafnia alvei strain NCTC8535 genome assembly, contig:

Gene Summary

Adenine Count

1230251 bp

Thymine Count

1228315 bp

Guanine Count

1165036 bp

Cytosine Count

1166554 bp

Genome Length

4790156 bp

Protein-coding Genes

4107 genes

Non-Coding Genes

376 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cell division atp-binding protein ftseNCTC8535_03388Not AvailablePositive3531615 - 353228324445.9
cell division protein ftsxNCTC8535_03389Not AvailablePositive3532276 - 353325335585.7
heat shock regulatory protein f33.4NCTC8535_03390Not AvailablePositive3533532 - 353438332355.4
acetyltransferase, gnat familyNCTC8535_03391Not AvailableNegative3534453 - 353486615685.6
leucine-specific-binding protein precursorNCTC8535_03392Not AvailablePositive3535284 - 353639639497.3
liv-i protein hNCTC8535_03393Not AvailablePositive3536619 - 353754532909.4
leucine/isoleucine/valine transporter permease subunitNCTC8535_03394Not AvailablePositive3537542 - 353881346034.9
lipopolysaccharide export system atp-binding protein lptbNCTC8535_03395Not AvailablePositive3538810 - 353958028352.7
liv-i protein fNCTC8535_03396Not AvailablePositive3539583 - 354028425643.2
glycerol-3-phosphate transporter periplasmic binding proteinNCTC8535_03397Not AvailablePositive3540474 - 354179648474.7

Displaying genes 3441 – 3450 of 4483 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

318 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da

Displaying 1–10 of 318 metabolites

Health Effects

Health ConditionRelationReference
Mild diseasesCausesPMC5615607
Bee septicemiaCausesPMC8729767
SepticemiaCausesPMC8729767

Displaying health effects 1 – 3 of 3 in total