Escherichia coli strain NCTC9706

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC9706 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. It typically resides in host-associated environments, demonstrating mobility due to the presence of flagella. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. This strain is notable for its pathogenicity, particularly in humans, where it is associated with a wide range of health effects. These include urinary tract infections (UTIs), gastrointestinal infections, septicemia, and even severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The diverse biotic relationships indicate a free-living nature while also being capable of infecting various hosts, including Homo sapiens, Gallus gallus (chickens), and Bos taurus (cattle), among others. The strain is characterized by having a single replicon and two membranes, which is typical for members of the Enterobacteriaceae family. The extensive list of hosts indicates a broad ecological niche, suggesting that E. coli NCTC9706 has adapted to interact with multiple species across various environments. Given its ability to cause significant health issues, understanding the ecological dynamics of this strain can provide insights into its transmission pathways and potential prevention strategies in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC9706

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC9706
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC9706 genome assembly, contig:

Gene Summary

Adenine Count

1356279 bp

Thymine Count

1353614 bp

Guanine Count

1396411 bp

Cytosine Count

1414637 bp

Genome Length

5520941 bp

Protein-coding Genes

4833 genes

Non-Coding Genes

706 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinNCTC9706_01943Not AvailablePositive1902878 - 19030516714.25
putative type iii effector proteinNCTC9706_01944Not AvailableNegative1903007 - 190414344203.7
putative type iii effector proteinNCTC9706_01945Not AvailableNegative1904201 - 19043957208.74
uncharacterised proteinNCTC9706_01946Not AvailablePositive1904497 - 19046495363.52
maltose regulon periplasmic proteinNCTC9706_01947Not AvailableNegative1904624 - 190554431917.2
maltoporin (maltose-inducible porin)NCTC9706_01948Not AvailableNegative1905696 - 190703349852.8
maltose/maltodextrin transporter atp-binding proteinNCTC9706_01949Not AvailableNegative1907108 - 190822340993.0
sugar abc transporterNCTC9706_01950Not AvailablePositive1908400 - 19084953190.97
maltose transport system, substrate-binding proteinNCTC9706_01951Not AvailablePositive1908588 - 190977843389.9
maltose transporter membrane proteinNCTC9706_01952Not AvailablePositive1909932 - 191147657016.6

Displaying genes 2391 – 2400 of 5539 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total