Escherichia coli strain NCTC9706

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC9706 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. It typically resides in host-associated environments, demonstrating mobility due to the presence of flagella. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. This strain is notable for its pathogenicity, particularly in humans, where it is associated with a wide range of health effects. These include urinary tract infections (UTIs), gastrointestinal infections, septicemia, and even severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The diverse biotic relationships indicate a free-living nature while also being capable of infecting various hosts, including Homo sapiens, Gallus gallus (chickens), and Bos taurus (cattle), among others. The strain is characterized by having a single replicon and two membranes, which is typical for members of the Enterobacteriaceae family. The extensive list of hosts indicates a broad ecological niche, suggesting that E. coli NCTC9706 has adapted to interact with multiple species across various environments. Given its ability to cause significant health issues, understanding the ecological dynamics of this strain can provide insights into its transmission pathways and potential prevention strategies in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC9706

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC9706
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC9706 genome assembly, contig:

Gene Summary

Adenine Count

1356279 bp

Thymine Count

1353614 bp

Guanine Count

1396411 bp

Cytosine Count

1414637 bp

Genome Length

5520941 bp

Protein-coding Genes

4833 genes

Non-Coding Genes

706 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein-export proteinNCTC9706_01097Not AvailableNegative1069269 - 107108365171.4
secyeg protein translocase auxillary subunitNCTC9706_01098Not AvailableNegative1071144 - 107147611887.9
pp_01039NCTC9706_01099Not AvailableNegative1071499 - 1072626Not Available
s-adenosylmethionine--trna ribosyltransferase-isomeraseNCTC9706_01100Not AvailableNegative1072682 - 107375239433.0
acyl carrier protein phosphodiesteraseNCTC9706_01101Not AvailablePositive1073845 - 107442622962.3
maltodextrin glucosidaseNCTC9706_01102Not AvailableNegative1074431 - 107624869148.9
proline-specific permeaseNCTC9706_01103Not AvailableNegative1076404 - 107777750218.8
branched chain amino acid transport system ii carrier proteinNCTC9706_01104Not AvailableNegative1077853 - 107917246211.5
phosphate regulon two-component system, sensor kinaseNCTC9706_01105Not AvailableNegative1079579 - 108087449633.4
phosphate regulon two-component system, response regulatorNCTC9706_01106Not AvailableNegative1080932 - 108162126435.0

Displaying genes 1661 – 1670 of 5539 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total