Escherichia coli strain NCTC9119

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC9119 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in various oxygen conditions. It typically arranges itself in singles or pairs and is motile due to the presence of flagella. This strain is mesophilic, with an optimal growth temperature of 37°C. NCTC9119 is host-associated and can be found in a wide array of biotic relationships, primarily as a free-living organism. Its known hosts include Homo sapiens, various livestock such as Bos taurus and Sus scrofa, and even plants like Solanum lycopersicum. This broad host range highlights the strain's ecological versatility. Clinically, E. coli NCTC9119 is associated with a variety of health effects, most notably urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It is linked to severe conditions such as pyogenic liver abscess, hemolytic uremic syndrome (HUS), and even complications leading to renal failure and colorectal cancer. The strain's pathogenicity specifically affects humans, underscoring its relevance in clinical microbiology. The ecological insight drawn from NCTC9119's host diversity and pathogenic potential indicates that this strain plays a significant role in both environmental and clinical contexts. Its ability to infect a wide range of organisms suggests a complex interplay between microbial ecology and human health, where E. coli can transition from a benign gut inhabitant to a pathogen under certain conditions. This duality emphasizes the importance of monitoring and understanding such strains to mitigate their health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC9119

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC9119
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC9119 genome assembly, contig:

Gene Summary

Adenine Count

1361440 bp

Thymine Count

1360809 bp

Guanine Count

1388860 bp

Cytosine Count

1385128 bp

Genome Length

5496237 bp

Protein-coding Genes

4788 genes

Non-Coding Genes

429 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative colanic biosynthesis udp-glucose lipid carrier transferaseNCTC9119_02008Not AvailablePositive2091168 - 209256252413.5
putative flippase (putative export protein)NCTC9119_02009Not AvailablePositive2092564 - 209404253728.0
transposaseNCTC9119_02010Not AvailableNegative2094179 - 209478123199.8
transposaseNCTC9119_02011Not AvailableNegative2095006 - 209552720154.3
ribonucleoside diphosphage reductase 1, beta subunit, b2NCTC9119_02012Not AvailablePositive2095543 - 209603418199.7
colanic acid biosynthesis proteinNCTC9119_02013Not AvailablePositive2096042 - 209732247355.4
putative colanic acid biosynthesis glycosyltransferaseNCTC9119_02014Not AvailablePositive2097319 - 209853945360.1
colanic acid biosynthesis proteinNCTC9119_02015Not AvailablePositive2098550 - 209994451170.7
utp--glucose-1-phosphate uridylyltransferase subunit galfNCTC9119_02016Not AvailablePositive2100119 - 210101232825.3
dtdp-d-glucose 4,6-dehydratase rmlbNCTC9119_02018Not AvailablePositive2101385 - 210247040550.5

Displaying genes 2321 – 2330 of 5217 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total