Escherichia coli strain NCTC9075

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC9075 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in various oxygen conditions. This strain is motile and possesses flagella, contributing to its ability to inhabit diverse environments, often associated with hosts such as Homo sapiens, Bos taurus, and Sus scrofa, among others. Notably, it has a single replicon and two membranes, characteristic of its cellular structure. NCTC9075 is mesophilic, with an optimal growth temperature of 37°C, reflecting its adaptation to warm-blooded hosts. It has been implicated in a range of health effects, primarily associated with urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). This strain is known to cause significant clinical diseases, including peritonitis, diarrhea, and sepsis, highlighting its pathogenic potential in humans and other animals. The extensive list of hosts indicates a broad ecological niche, suggesting that E. coli NCTC9075 can engage in various biotic relationships, including free-living states. Its presence in diverse species, from mammals to birds and even plants like Solanum lycopersicum, underscores its adaptability. This adaptability may facilitate the strain's transmission and survival across different environments, making it a significant concern in public health and veterinary medicine. The strain's role in serious health complications emphasizes the need for ongoing research and monitoring to mitigate its impact on human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC9075

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC9075
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC9075 genome assembly, contig:

Gene Summary

Adenine Count

1317193 bp

Thymine Count

1323193 bp

Guanine Count

1334825 bp

Cytosine Count

1329370 bp

Genome Length

5304581 bp

Protein-coding Genes

6223 genes

Non-Coding Genes

492 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinNCTC9075_00030Not AvailablePositive15116 - 1542410684.4
Tail fiber proteinNCTC9075_00031Not AvailablePositive15411 - 1586316511.4
Tail fiber assembly proteinNCTC9075_00032Not AvailablePositive15881 - 161028550.61
Tail fiber assembly protein gpuNCTC9075_00033Not AvailablePositive16162 - 163868141.53
Tail fiber assembly proteinNCTC9075_00034Not AvailableNegative16437 - 1697020631.4
Tail fiber fragmentNCTC9075_00035Not AvailableNegative17064 - 1799033291.6
Site-specific recombinaseNCTC9075_00036Not AvailablePositive18010 - 1856420789.4
AttrNot AvailableNot AvailablePositive33338 - 33349Not Available
Transcription regulatorNCTC9075_00052Not AvailableNegative28290 - 2894623881.8
uncharacterised proteinNCTC9075_00053Not AvailablePositive29120 - 2950614774.7

Displaying genes 21 – 30 of 6715 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total