Escherichia coli strain NCTC8179

Escherichia coli strain NCTC8179 is a Gram-negative, rod-shaped bacterium exhibiting mobility, facilitated by the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in various oxygen conditions. This strain is mesophilic, with an optimal growth temperature of 37°C. NCTC8179 is notable for its wide range of hosts, which includes various species such as Homo sapiens, Gallus gallus, Bos taurus, and several others across different taxa, including mammals, birds, and even plants like Solanum lycopersicum. This diversity in hosts reflects its adaptability and ecological versatility. The strain possesses a single replicon and is characterized by two membranes, typical of its classification within the Enterobacteriaceae family. Clinically, E. coli NCTC8179 is associated with numerous health effects, particularly in humans. It is implicated in conditions such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and various forms of colitis. The pathogenicity of this strain highlights its role as a significant contributor to foodborne illnesses and other health complications, such as hemolytic uremic syndrome (HUS) and septicemia. The free-living nature of NCTC8179, combined with its pathogenic potential, underscores its relevance in both ecological and clinical contexts. Its ability to cause serious health issues, particularly in vulnerable populations, emphasizes the importance of monitoring its prevalence and understanding its interactions within diverse environments.