Escherichia coli strain NCTC9117

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC9117 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and the presence of flagella, which contributes to its mobility. This strain typically resides in host-associated environments, reflecting its adaptability to various biological hosts, including Homo sapiens and other mammals, birds, and even certain plants like Solanum lycopersicum and Brassica oleracea var. italica. The optimal growth temperature for E. coli NCTC9117 is 37°C, placing it within the mesophilic temperature range. It has a single replicon and possesses two membranes, typical of the Gram-negative bacteria. This strain is known to have a wide range of biotic relationships, functioning as a free-living organism while also causing significant health effects in its hosts. E. coli NCTC9117 is associated with various health concerns, particularly in humans, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among others. It is also implicated in severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. The diverse pathogenicity of this strain highlights its role in both health and disease, emphasizing the need for careful monitoring in clinical and agricultural settings. Its ability to thrive in a variety of hosts and environments suggests a complex ecological niche, where it can influence not only the health of individual hosts but also broader ecological dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC9117

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC9117
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC9117 genome assembly, contig:

Gene Summary

Adenine Count

1262862 bp

Thymine Count

1261609 bp

Guanine Count

1303635 bp

Cytosine Count

1297581 bp

Genome Length

5125687 bp

Protein-coding Genes

5603 genes

Non-Coding Genes

575 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
integral membrane proteinNCTC9117_04919Not AvailableNegative3976891 - 397750522980.1
putative xanthine dehydrogenase, iron-sulfur binding subunitNCTC9117_04920Not AvailablePositive3977923 - 397861224342.1
putative xanthine dehydrogenase, fad-binding subunitNCTC9117_04921Not AvailablePositive3978609 - 397956533859.8
putative xanthine dehydrogenase, molybdenum-binding subunitNCTC9117_04922Not AvailablePositive3979562 - 398073141765.7
putative xanthine dehydrogenase, molybdenum-binding subunitNCTC9117_04923Not AvailablePositive3980850 - 398177932589.8
xanthine dehydrogenase accessory factorNCTC9117_04924Not AvailablePositive3981789 - 398315649910.9
integraseNCTC9117_04925Not AvailablePositive3983365 - 398469951044.6
uncharacterised proteinNCTC9117_04926Not AvailableNegative3984781 - 398549425923.3
uncharacterised proteinNCTC9117_04927Not AvailableNegative3985528 - 398736366822.5
uncharacterised proteinNCTC9117_04928Not AvailableNegative3987383 - 39875837478.14

Displaying genes 4931 – 4940 of 6178 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total