Escherichia coli strain NCTC13127

Escherichia coli strain NCTC13127 is a Gram-negative, rod-shaped bacterium that demonstrates mobility due to the presence of flagella. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, categorizing it as mesophilic. This strain is host-associated, exhibiting a biotic relationship that allows it to be free-living within various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and numerous other vertebrates and invertebrates. E. coli NCTC13127 is notably associated with a wide range of health effects, particularly in humans, where it is linked to urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. The strain's ability to cause diverse health issues underscores its pathogenic potential and significance in clinical microbiology. The extensive list of hosts indicates that this strain may play a role in various ecological niches, influencing both animal and human health. Its presence in multiple species, including domesticated animals and wild fauna, suggests a complex ecological interaction, potentially impacting food safety and zoonotic disease transmission. Understanding the pathogenic mechanisms of E. coli NCTC13127 could provide insights into preventing infections and managing health risks associated with this versatile bacterium.