Escherichia coli strain NCTC11022

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC11022 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, demonstrating mobility through the presence of flagella. This strain typically resides in host-associated environments, with an optimal growth temperature of 37°C, classifying it as mesophilic. E. coli NCTC11022 has a single replicon and consists of two membranes. This strain has a wide range of biotic relationships, being free-living and associated with various hosts, including Homo sapiens, Gallus gallus, Bos taurus, as well as several other mammals, birds, and even plants like Solanum lycopersicum and Brassica oleracea var. italica. The diverse host range indicates its adaptability and ecological significance. E. coli NCTC11022 is associated with numerous health effects, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemorrhagic colitis. Its pathogenicity primarily affects humans but extends to other animals, leading to various diseases such as peritonitis, diarrhea, and sepsis. The extensive list of health effects linked to this strain underscores its importance in both clinical and ecological contexts. Its ability to cause a range of infections highlights the need for continued vigilance in monitoring and managing E. coli strains, particularly in relation to food safety and public health. Understanding the ecological interactions of E. coli NCTC11022 can provide insights into its role in health and disease across multiple species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC11022

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC11022
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC11022 genome assembly, contig:

Gene Summary

Adenine Count

1250925 bp

Thymine Count

1246470 bp

Guanine Count

1274504 bp

Cytosine Count

1298500 bp

Genome Length

5070399 bp

Protein-coding Genes

4695 genes

Non-Coding Genes

522 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
biofilm formation regulatory protein bsssNCTC11022_00169Not AvailablePositive125370 - 1256249633.29
n-methyl-l-tryptophan oxidaseNCTC11022_00170Not AvailablePositive125739 - 12685740888.2
small protein involved in biofilm formation and acid stress responseNCTC11022_00171Not AvailablePositive126905 - 1270184719.1
putative cytochromeNCTC11022_00172Not AvailablePositive127280 - 12763013417.7
putative cytochromeNCTC11022_00173Not AvailablePositive127569 - 12784710010.2
protein ycei precursorNCTC11022_00174Not AvailablePositive127891 - 12842719508.7
rhodanase-like proteinNCTC11022_00175Not AvailableNegative128469 - 12952139713.3
lipid a biosynthesis lauroyl acyltransferaseNCTC11022_00176Not AvailablePositive129746 - 13066635408.9
drug efflux system protein mdtgNCTC11022_00177Not AvailablePositive130838 - 13206443870.0
acidic protein msybNCTC11022_00178Not AvailablePositive132147 - 13252114259.9

Displaying genes 561 – 570 of 5217 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total