Escherichia coli strain NCTC10865

Escherichia coli strain NCTC10865 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain exhibits mobility, facilitated by the presence of flagella, and typically forms pairs or exists as single cells. It is mesophilic, with an optimal growth temperature of 37°C. NCTC10865 is host-associated and displays a free-living biotic relationship. It has a diverse range of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, as well as other animals and even some plant species like Solanum lycopersicum and Brassica oleracea var. italica. This wide host range underscores its ecological adaptability. Clinically, NCTC10865 is associated with numerous health complications in humans, contributing to conditions such as urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It is implicated in severe health issues like hemorrhagic colitis and hemolytic uremic syndrome (HUS), highlighting its pathogenic nature. The strain can also cause infections in animals, including enteric diseases in calves and chronic mastitis in dairy cattle. The extensive range of health effects associated with E. coli NCTC10865 illustrates its significant role in both human and veterinary medicine. Its ability to inhabit various hosts and cause a multitude of diseases emphasizes the importance of monitoring and understanding this strain within ecological and public health contexts.