Escherichia coli strain NCTC7928

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC7928 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain exhibits mobility and possesses flagella, allowing it to move actively. It is predominantly found in host-associated habitats, including a diverse range of hosts such as Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals and vertebrates, as well as some invertebrates and plants. NCTC7928 operates optimally at a temperature of 37 °C, placing it within the mesophilic range. Its biological structure includes one replicon and two membranes, typical of Gram-negative bacteria. This strain is known for its pathogenicity in humans, being associated with numerous health effects. These include urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, septicemia, and various other serious conditions such as hemolytic uremic syndrome (HUS) and chronic mastitis. The extensive list of health effects linked to E. coli NCTC7928 underscores its significant role in human and animal health, highlighting its potential as a pathogen in both clinical settings and foodborne illness scenarios. This strain's capacity to infect a wide array of hosts suggests its ecological versatility and adaptability, emphasizing the importance of monitoring such bacteria in public health and agricultural contexts to mitigate risks associated with infections and outbreaks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC7928

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC7928
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC7928 genome assembly, contig:

Gene Summary

Adenine Count

1349208 bp

Thymine Count

1347965 bp

Guanine Count

1384725 bp

Cytosine Count

1386284 bp

Genome Length

5468182 bp

Protein-coding Genes

6303 genes

Non-Coding Genes

847 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Bacteriophage major capsid proteinNCTC7928_00124Not AvailableNegative95798 - 9610011462.2
Bacteriophage head decoration proteinNCTC7928_00125Not AvailableNegative96158 - 963767516.94
Bacteriophage prohead proteaseNCTC7928_00126Not AvailableNegative96544 - 9755735200.0
Bacteriophage prohead proteaseNCTC7928_00127Not AvailableNegative97740 - 9805111014.4
Bacteriophage portal proteinNCTC7928_00128Not AvailableNegative98041 - 9911440512.8
Bacteriophage portal proteinNCTC7928_00129Not AvailableNegative99134 - 9942710922.8
Bacteriophage portal proteinNCTC7928_00130Not AvailableNegative99457 - 996336021.25
Bacteriophage head-to-tail joining proteinNCTC7928_00131Not AvailableNegative99630 - 998397602.15
Dna packaging proteinNCTC7928_00132Not AvailableNegative100009 - 10105239481.8
Dna packaging proteinNCTC7928_00133Not AvailableNegative101106 - 10175324176.0

Displaying genes 1 – 10 of 7150 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total