Escherichia coli strain NCTC10082

Escherichia coli strain NCTC10082 is a gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, typically at an optimal temperature of 37°C, indicating its mesophilic nature. It is known to exist in pairs or as single cells and has two membranes surrounding its cellular structure. NCTC10082 is primarily associated with various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and multiple other vertebrates and invertebrates. Its capability to inhabit diverse organisms highlights its ecological versatility. In terms of pathogenicity, this strain is notorious for causing a range of health issues, particularly in humans. It is implicated in urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's association with foodborne infections further underscores its potential impact on public health. Given its free-living biotic relationship and ability to infect multiple hosts, E. coli NCTC10082 serves as an important model for studying bacterial pathogenicity and host interactions. Its role in various diseases emphasizes the necessity for ongoing research into its mechanisms of infection and transmission, which are crucial for developing effective prevention and treatment strategies.