Escherichia coli strain NCTC9037

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC9037 is a gram-negative, rod-shaped bacterium that resides primarily in host-associated environments. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic conditions. This strain exhibits mobility due to the presence of flagella and typically forms pairs or singles. The optimal growth temperature for E. coli NCTC9037 is 37°C, placing it within the mesophilic temperature range. It has a single replicon and is characterized by having two membranes, consistent with its classification as a member of the Enterobacteriaceae family. This strain has a diverse range of biotic relationships, being free-living yet capable of associating with numerous hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other vertebrates and invertebrates. Notably, it is associated with a variety of health effects in humans, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS), neonatal meningitis, and septicemia. The pathogenic nature of E. coli NCTC9037 highlights its importance in clinical microbiology and public health, particularly concerning foodborne diseases and infections in both humans and animals. Its ability to cause a wide range of illnesses underscores the ecological role this strain plays, not only within its hosts but also in the broader context of environmental and health dynamics. Understanding its pathogenicity and host interactions can inform strategies for disease prevention and management in both clinical and agricultural settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC9037

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC9037
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC9037 genome assembly, contig:

Gene Summary

Adenine Count

1264756 bp

Thymine Count

1263356 bp

Guanine Count

1310135 bp

Cytosine Count

1305339 bp

Genome Length

5143586 bp

Protein-coding Genes

4430 genes

Non-Coding Genes

556 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
inner membrane proteinNCTC9037_03880Not AvailableNegative3873407 - 387378414771.0
primosomal replication protein nNCTC9037_03881Not AvailablePositive3873854 - 387438120376.5
small protein involved in the cell envelope stress responseNCTC9037_03882Not AvailablePositive3874395 - 38745566025.2
potassium efflux proteinNCTC9037_03883Not AvailableNegative3874768 - 3878130127223.0
acrab operon repressorNCTC9037_03884Not AvailableNegative3878258 - 387890524768.1
acriflavin resistance protein aNCTC9037_03885Not AvailablePositive3879047 - 388024042199.1
acriflavin resistance protein bNCTC9037_03886Not AvailablePositive3880263 - 3883412113580.0
putative cytoplasmic proteinNCTC9037_03887Not AvailablePositive3883958 - 388433214558.1
hemolysin expression-modulating proteinNCTC9037_03888Not AvailablePositive3884358 - 38845768628.46
maltose o-acetyltransferaseNCTC9037_03889Not AvailablePositive3884748 - 388529920097.2

Displaying genes 3851 – 3860 of 4986 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total