Escherichia coli strain NCTC10767

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC10767 is a Gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism and possesses flagella, allowing for mobility. This strain is mesophilic, with an optimal growth temperature of 37°C. It is characterized by its ability to exist in pairs or as single cells, and it has a biotic relationship that is classified as free-living, although it is host-associated. NCTC10767 is known to inhabit a range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals, birds, and even plants such as Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). This broad host range suggests a versatile ecological role, potentially contributing to both symbiotic and pathogenic interactions. The strain is notably pathogenic to humans, associated with a range of health effects including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among others. It can lead to severe conditions such as hemolytic uremic syndrome, septicemia, and even colorectal cancer. The ability of NCTC10767 to affect diverse hosts indicates its potential for transmission and impact on both human health and animal husbandry. Understanding the pathogenicity and ecological interactions of E. coli strain NCTC10767 is crucial for developing strategies to manage its health impacts, especially in clinical settings where its presence can lead to significant health concerns.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC10767

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC10767
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC10767 genome assembly, contig:

Gene Summary

Adenine Count

1360598 bp

Thymine Count

1369659 bp

Guanine Count

1433902 bp

Cytosine Count

1365701 bp

Genome Length

5529860 bp

Protein-coding Genes

5043 genes

Non-Coding Genes

909 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
yeca family proteinNCTC10767_02156Not AvailablePositive2003502 - 200408021230.8
proline aminopeptidase iiNCTC10767_02157Not AvailablePositive2004106 - 200488829782.0
proline aminopeptidase iiNCTC10767_02158Not AvailablePositive2004863 - 20050878459.28
proline aminopeptidase iiNCTC10767_02159Not AvailablePositive2005069 - 200540712379.0
2-octaprenyl-6-methoxyphenol hydroxylaseNCTC10767_02160Not AvailablePositive2005427 - 200586114883.2
2-octaprenyl-6-methoxyphenol hydroxylaseNCTC10767_02161Not AvailablePositive2005879 - 200664627963.6
putative monooxygenaseNCTC10767_02162Not AvailablePositive2006628 - 200783044247.2
aminomethyltransferase (glycine cleavage system protein)NCTC10767_02163Not AvailablePositive2008277 - 200937140151.0
glycine cleavage system protein hNCTC10767_02164Not AvailablePositive2009395 - 200978413825.9
glycine dehydrogenaseNCTC10767_02165Not AvailablePositive2009902 - 2012775104299.0

Displaying genes 2891 – 2900 of 5952 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total