Klebsiella pneumoniae strain 4300STDY6470422

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 4300STDY6470422 is a Gram-negative, rod-shaped bacterium that typically exists in chains, pairs, or as single cells. This strain is classified as a chemoheterotroph, utilizing organic compounds as its energy source, and it exhibits facultative anaerobic respiration, allowing it to thrive in both aerobic and anaerobic environments. It possesses flagella, which contributes to its mobility, and it is mesophilic, with an optimal growth temperature of 37°C. This strain is notably pathogenic to humans and has been associated with a range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It has also been implicated in conditions such as liver abscesses, meningitis, and sepsis. The broad host range of Klebsiella pneumoniae strain 4300STDY6470422 extends beyond humans to include various species such as Gallus gallus (chickens), Danio rerio (zebrafish), and Sus scrofa (pigs), indicating its ecological versatility and ability to adapt to diverse environments. Given its pathogenic potential and association with multiple hosts, this strain exemplifies the importance of monitoring Klebsiella pneumoniae in clinical settings. Its ability to cause serious infections in humans and other species highlights the interconnectedness of health across different organisms and the significance of understanding microbial interactions in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 4300STDY6470422

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 4300STDY6470422
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 4300STDY6470422 genome assembly,

Gene Summary

Adenine Count

1238937 bp

Thymine Count

1234691 bp

Guanine Count

1622592 bp

Cytosine Count

1649226 bp

Genome Length

5748011 bp

Protein-coding Genes

5171 genes

Non-Coding Genes

164 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Kila-n domain-containing proteinSAMEA4364603_05074Not AvailableNegative5388314 - 538884419686.7
Tail proteinSAMEA4364603_05075Not AvailableNegative5389037 - 538934210954.0
Tail assembly chaperoneSAMEA4364603_05076Not AvailableNegative5389345 - 538974915021.0
Major tail subunitSAMEA4364603_05077Not AvailableNegative5389780 - 539048424458.7
Hypothetical proteinSAMEA4364603_05078Not AvailableNegative5390541 - 539088812557.9
Gp10SAMEA4364603_05079Not AvailableNegative5390885 - 539133416710.0
uncharacterised proteinSAMEA4364603_05080Not AvailablePositive5391646 - 539212817918.6
uncharacterised proteinSAMEA4364603_05081Not AvailableNegative5392020 - 53922749072.74
Major capsid proteinSAMEA4364603_05082Not AvailableNegative5392320 - 539354044287.8
Putative prohead proteaseSAMEA4364603_05083Not AvailableNegative5393550 - 539425726055.8

Displaying genes 41 – 50 of 5335 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1257 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da

Displaying 1–10 of 1257 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total