Escherichia coli strain VREC0374

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain VREC0374 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, thriving optimally at 37°C within a mesophilic temperature range. This strain is motile, possessing flagella, and is characterized by a cell arrangement that includes pairs and singles. It has a biotic relationship classified as free-living, indicating its ability to exist independently in various environments. The strain has a significant host range, affecting Homo sapiens, various livestock such as Bos taurus and Sus scrofa, and several other organisms, including birds, mammals, and even plants like Solanum lycopersicum and Brassica oleracea var. italica. This diverse array of hosts suggests that E. coli VREC0374 can adapt to different ecological niches, which may facilitate its transmission and survival in varied environments. Clinically, VREC0374 is associated with a range of health effects, primarily in humans, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions like septicemia and hemolytic uremic syndrome (HUS). Its pathogenicity underscores its potential impact on human health and agriculture, highlighting the importance of monitoring and understanding such strains in both clinical and environmental contexts. The ability of E. coli VREC0374 to inhabit multiple hosts and its association with numerous health issues suggest that it plays a significant role in both human and animal health, as well as in the ecology of microbial communities, particularly in relation to disease dynamics and transmission pathways.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain VREC0374

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain VREC0374
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain VREC0374 genome assembly, contig:

Gene Summary

Adenine Count

1347849 bp

Thymine Count

1349174 bp

Guanine Count

1357668 bp

Cytosine Count

1356575 bp

Genome Length

5412071 bp

Protein-coding Genes

4839 genes

Non-Coding Genes

458 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3753097_00363Not AvailableNegative376654 - 37716918943.8
Hypothetical proteinSAMEA3753097_00364Not AvailablePositive377640 - 37800213107.6
Hypothetical proteinSAMEA3753097_00365Not AvailablePositive378068 - 37889230444.1
Hypothetical proteinSAMEA3753097_00366Not AvailablePositive379020 - 37955620272.5
Hypothetical proteinSAMEA3753097_00367Not AvailablePositive379547 - 3797989491.5
Hypothetical proteinSAMEA3753097_00368Not AvailablePositive379909 - 38021412161.5
IntegraseSAMEA3753097_00369Not AvailablePositive380441 - 38160445004.4
AttrNot AvailableNot AvailablePositive391841 - 391853Not Available
AttlNot AvailableNot AvailablePositive1647163 - 1647182Not Available
Bifunctional trna (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase mnmd/fad-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase mnmcSAMEA3753097_01578Not AvailableNegative1647216 - 164922274480.2

Displaying genes 81 – 90 of 5297 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total