Escherichia coli strain VREC0307

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain VREC0307 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile, characterized by the presence of flagella, and typically found in pairs or as single cells. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of its primary host, Homo sapiens. VREC0307 has a diverse range of hosts, including various mammals, birds, and even some plants, indicating its adaptability and ecological versatility. Notable hosts include domestic animals such as Gallus gallus (chickens) and Sus scrofa (pigs), as well as wild species like Cervus elaphus (deer) and Canis lupus familiaris (dogs). This broad host range suggests that VREC0307 can occupy multiple ecological niches, potentially influencing both animal health and agricultural practices. The strain is associated with numerous health effects, particularly in humans, where it is linked to conditions such as urinary tract infections (UTIs), gastrointestinal infections, and severe illnesses like neonatal meningitis and hemolytic uremic syndrome (HUS). These pathogenic traits highlight the strain's potential as a significant public health concern. In summary, Escherichia coli strain VREC0307 exemplifies the complex interplay between microbial life and host organisms. Its ability to thrive in various environments and its association with a wide range of diseases underscore the importance of monitoring such strains in both medical and ecological contexts, particularly in settings where human and animal interactions are prevalent.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain VREC0307

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain VREC0307
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain VREC0307 genome assembly, contig:

Gene Summary

Adenine Count

1290844 bp

Thymine Count

1292415 bp

Guanine Count

1324906 bp

Cytosine Count

1324109 bp

Genome Length

5233042 bp

Protein-coding Genes

4642 genes

Non-Coding Genes

368 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Holin proteinSAMEA3472147_00737Not AvailableNegative809229 - 8094357394.97
Antitermination protein qSAMEA3472147_00739Not AvailableNegative811090 - 81141312286.0
Hypothetical proteinSAMEA3472147_02040Not AvailablePositive2173334 - 217423933875.9
AttlNot AvailableNot AvailablePositive2173470 - 2173483Not Available
Hypothetical proteinSAMEA3472147_02041Not AvailablePositive2174247 - 217482221812.0
Antiterminator protein qSAMEA3472147_02042Not AvailableNegative2174815 - 217517713480.5
Hypothetical proteinSAMEA3472147_02043Not AvailableNegative2175195 - 217618437135.9
Klia-n domain proteinSAMEA3472147_02044Not AvailableNegative2176192 - 217698929759.8
Holliday junction resolvaseSAMEA3472147_02045Not AvailableNegative2177009 - 217739814102.0
Lexa dna binding domain proteinSAMEA3472147_02046Not AvailableNegative2177395 - 217772112093.7

Displaying genes 31 – 40 of 5010 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total