Escherichia coli strain VREC0386

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain VREC0386 is a Gram-negative, rod-shaped bacterium that exhibits a cell arrangement typically found in pairs or singles. It is classified as a facultative anaerobe, meaning it can thrive in both aerobic and anaerobic environments, and it possesses flagella, which enable mobility. This strain has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. VREC0386 is notably free-living and has been isolated from a variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and many others across different taxonomic groups. These hosts include mammals, birds, and even plants like Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). Such a diverse range of hosts indicates its ecological versatility and potential for cross-species transmission. The health effects associated with strain VREC0386 are significant, as it is implicated in numerous diseases, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It can lead to severe conditions such as hemolytic uremic syndrome (HUS), peritonitis, and various forms of food poisoning. The strain's pathogenicity in humans highlights its role as a major concern in clinical microbiology and public health. Overall, the presence of E. coli strain VREC0386 in diverse hosts and its association with a wide array of health issues emphasize its ecological significance and the need for ongoing surveillance to mitigate potential outbreaks and health impacts on both human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain VREC0386

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain VREC0386
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain VREC0386 genome assembly, contig:

Gene Summary

Adenine Count

1420901 bp

Thymine Count

1429063 bp

Guanine Count

1451151 bp

Cytosine Count

1431767 bp

Genome Length

5733849 bp

Protein-coding Genes

5145 genes

Non-Coding Genes

448 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterized conserved proteinSAMEA3753290_01874Not AvailableNegative1976680 - 197714117319.4
rhs element vgr proteinSAMEA3753290_01875Not AvailableNegative1977169 - 197907071355.0
sensor kinase cussSAMEA3753290_01876Not AvailableNegative1979807 - 198125554063.5
two-component system response regulatorSAMEA3753290_01877Not AvailableNegative1981245 - 198192825396.1
copper/silver efflux system outer membrane protein cuscSAMEA3753290_01878Not AvailablePositive1982085 - 198346750714.9
cation efflux system proteinSAMEA3753290_01879Not AvailablePositive1983491 - 198382312281.9
cation efflux system proteinSAMEA3753290_01880Not AvailablePositive1983839 - 198506244335.4
cation efflux system proteinSAMEA3753290_01881Not AvailablePositive1985074 - 1988217114714.0
phenylalanine transporterSAMEA3753290_01882Not AvailablePositive1988319 - 198969550648.3
putative mechanosensitive ion channel proteinSAMEA3753290_01883Not AvailableNegative1989763 - 199101046619.5

Displaying genes 2211 – 2220 of 5593 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total