Escherichia coli strain VREC0506

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain VREC0506 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is associated with a wide range of hosts, including Homo sapiens, various livestock species (e.g., Bos taurus, Sus scrofa), and numerous other organisms spanning multiple taxa such as Aves, Canis lupus familiaris, and Apis mellifera. It thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. VREC0506 has a biotic relationship classified as free-living and possesses a single replicon with a structure consisting of two membranes. Notably, this strain is implicated in a variety of health effects, particularly in humans, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as septicemia and hemolytic uremic syndrome (HUS). The strain is also linked to foodborne infections and has been associated with complications like neonatal meningitis and peritonitis. The extensive host range and significant pathogenic potential of E. coli strain VREC0506 underscore its ecological versatility and importance in both environmental and clinical microbiology. This strain exemplifies the complex interactions between microbial pathogens and their hosts, highlighting the potential for zoonotic transmission and the importance of monitoring such strains in public health and food safety contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain VREC0506

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain VREC0506
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain VREC0506 genome assembly, contig:

Gene Summary

Adenine Count

1330351 bp

Thymine Count

1331131 bp

Guanine Count

1348395 bp

Cytosine Count

1373263 bp

Genome Length

5383453 bp

Protein-coding Genes

4777 genes

Non-Coding Genes

397 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Replication initiation proteinSAMEA3752553_00477Not AvailablePositive519609 - 52047233342.9
Nonstructural proteinSAMEA3752553_00478Not AvailablePositive520459 - 52072810281.1
Minor capsid proteinSAMEA3752553_00479Not AvailablePositive520709 - 52122118784.6
Capsid proteinSAMEA3752553_00480Not AvailablePositive521367 - 52304062487.4
Dna pilot proteinSAMEA3752553_00481Not AvailablePositive523125 - 52389527011.8
Nonstructural proteinSAMEA3752553_00482Not AvailablePositive523898 - 5240174770.98
protein hipaSAMEA3752553_00483Not AvailableNegative524139 - 52546149424.9
Transcription regulatorSAMEA3752553_00484Not AvailableNegative525461 - 52572710047.9
AttlNot AvailableNot AvailablePositive553323 - 553334Not Available
AttlNot AvailableNot AvailablePositive563983 - 563994Not Available

Displaying genes 1 – 10 of 5174 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Bloody diarrheaCausesPMC9147554
Hemorrhagic colitisCausesPMC9147554
Hemolytic uremic syndromeCausesPMC9147554
HusCausesPMC9147554
Calf diarrheaCausesPMC9861278
SbpCausesPMC10556727
IeCausesPMC10972404
Pregnancy lossCausesPMC11597549
Neonatal deathCausesPMC11597549
AbortionCausesPMC11597549

Displaying health effects 41 – 50 of 103 in total