Escherichia coli strain VREC0353

Escherichia coli strain VREC0353 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and possesses flagella, allowing for mobility. This strain is typically found in host-associated habitats, indicating a close relationship with various organisms, including Homo sapiens, Gallus gallus, Bos taurus, and other vertebrates as well as some plants like Solanum lycopersicum. The strain thrives optimally at 37°C, falling within a mesophilic temperature range. It is characterized by having a single replicon and two membranes, which is typical of Gram-negative bacteria. VREC0353 exhibits a free-living biotic relationship, suggesting it can exist independently of its hosts under certain conditions. Clinically, E. coli strain VREC0353 is associated with a wide range of health effects, particularly in humans, where it can cause urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as septicemia and hemolytic uremic syndrome (HUS). The strain is also linked to neonatal meningitis and various forms of diarrhea, including hemorrhagic colitis. Its pathogenicity highlights the potential for significant health impacts in both humans and animals, emphasizing the importance of monitoring and managing infections caused by this strain. The diverse range of hosts, including mammals, birds, and even some insects, suggests that E. coli strain VREC0353 plays a versatile ecological role. This adaptability may facilitate the bacterium's persistence in various environments, reinforcing its significance in both health and disease across multiple species.